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Single domain camel antibodies: current status.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Single domain camel antibodies: current status
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
antibody
1 reference
based on heuristic
inferred from title
Camelus
1 reference
based on heuristic
inferred from title
author
Serge Muyldermans
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
S Muyldermans
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
retrieved
28 June 2017
publication date
1 June 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Journal of Biotechnology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
74
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
277-302
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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7 January 2021
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Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs
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Affinity improvement of single antibody VH domains: residues in all three hypervariable regions affect antigen binding
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Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability
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Selection of high-affinity phage antibodies from phage display libraries
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A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies
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Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme
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Recent advances in the large-scale production of antibody fragments using lower eukaryotic microorganisms
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Isolation of antigen specific llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae
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7 January 2021
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Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
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A comparison of strategies to stabilize immunoglobulin Fv-fragments
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Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs
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Human antibodies from transgenic mice
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Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features
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Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains
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Antibody phage display technology and its applications.
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Recombinant antibody fragments
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7 January 2021
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Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
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7 January 2021
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Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
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Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
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Continuous cultures of fused cells secreting antibody of predefined specificity
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Therapeutic peptides revisited
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Systematic exploration of the antigen binding activity of synthetic peptides isolated from the variable regions of immunoglobulins
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Potent enzyme inhibitors derived from dromedary heavy-chain antibodies
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Elbow motion in the immunoglobulins involves a molecular ball-and-socket joint
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Comparative properties of the single chain antibody and Fv derivatives of mAb 4-4-20. Relationship between interdomain interactions and the high affinity for fluorescein ligand
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By-passing immunization. Human antibodies from V-gene libraries displayed on phage
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Affinity selection of a camelized V(H) domain antibody inhibitor of hepatitis C virus NS3 protease
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7 January 2021
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Both DNA strands of antibody genes are hypermutation targets
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Conformations of the third hypervariable region in the VH domain of immunoglobulins
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Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains
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Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies
1 reference
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7 January 2021
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Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire
1 reference
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The specific variable domain of camel heavy-chain antibodies is encoded in the germline
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7 January 2021
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Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.
1 reference
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7 January 2021
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A possible procedure for reducing the immunogenicity of antibody variable domains while preserving their ligand-binding properties
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Anatomy of the antibody molecule
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X-ray crystallography of antibodies.
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Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.
1 reference
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The power of clonal selection
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An antibody single-domain phage display library of a native heavy chain variable region: isolation of functional single-domain VH molecules with a unique interface.
1 reference
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7 January 2021
based on heuristic
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Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D region
1 reference
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7 January 2021
based on heuristic
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Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain
1 reference
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7 January 2021
based on heuristic
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Reshaping human antibodies for therapy
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7 January 2021
based on heuristic
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Single domain antibodies: comparison of camel VH and camelised human VH domains
1 reference
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7 January 2021
based on heuristic
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Intracellular antibodies (intrabodies) for gene therapy of infectious diseases
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7 January 2021
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Heavy Chain Diseases: Current Findings and Concepts
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Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate
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7 January 2021
based on heuristic
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Redefining the minimal antigen-binding fragment
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7 January 2021
based on heuristic
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Structural classification of CDR-H3 in antibodies
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7 January 2021
based on heuristic
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H3-rules: identification of CDR-H3 structures in antibodies
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7 January 2021
based on heuristic
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Bacterial expression of immunoglobulin fragments
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7 January 2021
based on heuristic
inferred from DOI database lookup
Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
1 reference
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https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of a llama heavy chain variable domain
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Camelid heavy-chain variable domains provide efficient combining sites to haptens
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
"Peptabody": a new type of high avidity binding protein
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic generation of antibody diversity
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7 January 2021
based on heuristic
inferred from DOI database lookup
Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of immune responses and molecular cloning of the heavy chain antibody repertoire of Lama glama
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of antibodies for intracellular function using a two-hybrid in vivo system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of llama VH sequences from conventional and heavy chain antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Making antibodies by phage display technology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Man-made antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Length distribution of CDRH3 in antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1389-0352%2801%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1389-0352(01)00021-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
11526908
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11526908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11526908%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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