(Q31012256)

English

Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

drug interaction

0 references

Aleksandra Galetin

object named as

Aleksandra Galetin

3

0 references

author name string

Hayley S Brown

1

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Kiyomi Ito

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

J Brian Houston

4

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

language of work or name

0 references

publication date

1 November 2005

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

60

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

508-518

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Role of itraconazole metabolites in CYP3A4 inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Reaction phenotyping in drug discovery: moving forward with confidence?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Inhibition-based metabolic drug-drug interactions: predictions from in vitro data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Sense and nonsense in the prediction of drug-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--towards a consensus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

In vitro approaches to predicting drug interactions in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Clinical pharmacokinetics of fluconazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Clinical pharmacokinetics of selective serotonin reuptake inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Clinical pharmacokinetics of fluvoxamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Some suggestions for measuring predictive performance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Clinical pharmacokinetics of quinidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Influence of food on the pharmacokinetics of ketoconazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

The pharmacokinetics of midazolam in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Felodipine kinetics in healthy men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Pharmacokinetics of itraconazole following oral administration to normal volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Pharmacokinetics of the newer benzodiazepines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Genetic factors influencing the metabolism of tolbutamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Quinidine kinetics after a single oral dose in relation to the sparteine oxidation polymorphism in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Felodipine Clinical Pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884945

21 June 2018

Impact of parallel pathways of drug elimination and multiple cytochrome P450 involvement on drug-drug interactions: CYP2D6 paradigm.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02483.X

21 January 2018

The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02483.X

21 January 2018

Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02483.X

21 January 2018

'In silico' simulations to assess the 'in vivo' consequences of 'in vitro' metabolic drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemistry of aromatic phenytoin hydroxylation in various drug hydroxylation phenotypes in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of quinidine in humans after intravenous, intramuscular and oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ketoconazole in normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nifedipine: kinetics and dynamics in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Warfarin-fluconazole. III. A rational approach to management of a metabolically based drug interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16236041

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2005.02483.X

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

ResearchGate publication ID

0 references

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