(Q31034056)

20 September 2017

Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA (English)

1 reference

20 September 2017

Noah P Zimmerman

1

1 reference

20 September 2017

Suresh N Kumar

series ordinal

2

1 reference

20 September 2017

Jerrold R Turner

series ordinal

3

1 reference

20 September 2017

Michael B Dwinell

series ordinal

4

1 reference

20 September 2017

12 October 2011

1 reference

Inflammatory Bowel Diseases

20 September 2017

1 reference

20 September 2017

18

1 reference

20 September 2017

6

1 reference

20 September 2017

1081-1091

1 reference

describes a project that uses

20 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3258471/fullTextXML

inferred from PubMed Central ID database lookup

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The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.

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Cytoskeletal regulation of epithelial barrier function during inflammation

21 June 2018

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The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease

21 June 2018

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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

21 June 2018

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Roflumilast in chronic obstructive pulmonary disease: evidence from large trials

21 June 2018

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Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis

21 June 2018

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Disruption of the Cox-1 gene slows repair of microscopic lesions in the mouse gastric epithelium

21 June 2018

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Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort

21 June 2018

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Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia.

21 June 2018

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Therapeutic benefit of PDE4 inhibitors in inflammatory diseases.

21 June 2018

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cAMP signaling in leukocyte transendothelial migration

21 June 2018

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Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

21 June 2018

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Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application

21 June 2018

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Spatiotemporal dynamics of RhoA activity in migrating cells

21 June 2018

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The cross talk between protein kinase A- and RhoA-mediated signaling in cancer cells

21 June 2018

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Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

21 June 2018

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L-selectin: mechanisms and physiological significance of ectodomain cleavage.

21 June 2018

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Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure.

21 June 2018

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Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease

21 June 2018

1 reference

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CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity

21 June 2018

1 reference

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PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease

21 June 2018

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SDF-1/CXCL12 regulates cAMP production and ion transport in intestinal epithelial cells via CXCR4.

21 June 2018

1 reference

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Cyclic nucleotides promote monocyte differentiation toward a DC-SIGN+ (CD209) intermediate cell and impair differentiation into dendritic cells

21 June 2018

1 reference

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Mucosal repair in the gastrointestinal tract

21 June 2018

1 reference

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Immunobiology of epithelial chemokines in the intestinal mucosa

21 June 2018

1 reference

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Rho GTPases in cell biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Rho GTPases and cell migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Dextran sulfate sodium-induced colonic histopathology, but not altered epithelial ion transport, is reduced by inhibition of phosphodiesterase activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Review article: healing after inflammatory injury--coordination of a regulatory peptide network

21 June 2018

1 reference

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Intestinal restitution: progression of actin cytoskeleton rearrangements and integrin function in a model of epithelial wound healing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Rho proteins play a critical role in cell migration during the early phase of mucosal restitution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Restitution of the surface epithelium of the in vitro frog gastric mucosa after damage with hyperosmolar sodium chloride. Morphologic and physiologic characteristics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Intestinal permeability in children with Crohn's disease and coeliac disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Rapid epithelial restitution of the rat gastric mucosa after ethanol injury.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Gastrointestinal cell plasma membrane wounding and resealing in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Intestinal epithelial restitution. Characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Migration of IEC-6 cells: a model for mucosal healing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Microtubule dynamics and Rac-1 signaling independently regulate barrier function in lung epithelial cells.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Selective inhibition of phosphodiesterase-4 ameliorates chronic colitis and prevents intestinal fibrosis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Opposite effect of cAMP signaling in endothelial barriers of different origin

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Protein kinase A attenuates endothelial cell barrier dysfunction induced by microtubule disassembly

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

The burden of selected digestive diseases in the United States.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Rapid barrier restitution in an in vitro model of intestinal epithelial injury

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258471

Healing of Gastrointestinal Mucosa: Involvement of Polyamines

25 November 2018

1 reference

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

12 December 2020

Inhibition of PAF-induced expression of CD11b and shedding of L-selectin on human neutrophils and eosinophils by the type IV selective PDE inhibitor, rolipram

1 reference

12 December 2020

Specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice

1 reference

12 December 2020

Both protein kinase A and exchange protein activated by cAMP coordinate adhesion of human vascular endothelial cells

1 reference

12 December 2020

Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors

1 reference

12 December 2020

Intestinal permeability and the prediction of relapse in Crohn's disease

1 reference

12 December 2020

A human colonic tumor cell line that maintains vectorial electrolyte transport

1 reference

12 December 2020

Intestinal permeability in long-term follow-up of patients with celiac disease on a gluten-free diet

1 reference

12 December 2020

Identifiers

DOI

10.1002/IBD.21898

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

21993975

1 reference