(Q43183443)

English

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner

scientific article published on 26 January 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

1 reference

based on heuristic

inferred from title

Angélica T Vieira

5

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Cristiana C. Garcia

object named as

Cristiana C Garcia

9

0 references

Remo Castro Russo

object named as

Remo C Russo

8

0 references

Mauro M Teixeira

14

object named as

Mauro M Teixeira

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

author name string

Lirlândia P Sousa

1

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Fernando Lopes

2

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Douglas M Silva

3

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Luciana P Tavares

4

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Bárbara M Rezende

6

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Aline F Carmo

7

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Cláudio A Bonjardim

10

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Ana L Alessandri

11

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Adriano G Rossi

12

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Vanessa Pinho

13

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

publication date

26 January 2010

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Europe PubMed Central

PubMed publication ID

15 November 2017

Journal of Leukocyte Biology

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

87

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Europe PubMed Central

PubMed publication ID

15 November 2017

5

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Europe PubMed Central

PubMed publication ID

15 November 2017

895-904

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Cyclic AMP: master regulator of innate immune cell function.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Inhibition of cAMP degradation improves regulatory T cell-mediated suppression

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

cAMP protects neutrophils against TNF-alpha-induced apoptosis by activation of cAMP-dependent protein kinase, independently of exchange protein directly activated by cAMP (Epac).

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Regulation of granulocyte apoptosis by NF-kappaB.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Signalling through Class I PI3Ks in mammalian cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Regulation of granulocyte apoptosis by phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Regulation of neutrophil apoptosis by modulation of PKB/Akt activation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Plasminogen/plasmin regulates alpha-enolase expression through the MEK/ERK pathway

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Regulation of neutrophil apoptosis by Mcl-1.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Granulocyte apoptosis in the pathogenesis and resolution of lung disease

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

The activation of Akt/PKB signaling pathway and cell survival.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Nuclear factor-kappaB regulates inflammatory cell apoptosis and phagocytosis in rat carrageenin-sponge implant model

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Novel biphasic role for lymphocytes revealed during resolving inflammation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Phosphodiesterase type 4 inhibitor suppresses expression of anti-apoptotic members of the Bcl-2 family in B-CLL cells and induces caspase-dependent apoptosis.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

PDE4 inhibitors activate a mitochondrial apoptotic pathway in chronic lymphocytic leukemia cells that is regulated by protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Pharmacological PKA inhibition: all may not be what it seems

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT-dependent apoptosis in diffuse large B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Possible new role for NF-kappaB in the resolution of inflammation.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0809540

21 January 2018

Identifiers

10.1189/JLB.0809540

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

ResearchGate publication ID

0 references

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