(Q31074647)

28 June 2017

MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMR. (English)

1 reference

28 June 2017

Adrian Bird

3

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Alan R. Clarke

object named as

Alan R Clarke

series ordinal

4

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Owen J Sansom

object named as

Owen J Sansom

series ordinal

1

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author name string

Stefan M Bishop

series ordinal

2

1 reference

PubMed ID

15184874

28 June 2017

language of work or name

English

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publication date

1 July 2004

1 reference

28 June 2017

1 reference

28 June 2017

23

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28 June 2017

5693-5696

1 reference

28 June 2017

33

1 reference

Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations

28 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

Mammalian DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

P53 null mice: damaging the hypothesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

Sequence interruptions confer differential stability at microsatellite alleles in mismatch repair-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Female embryonic lethality in mice nullizygous for both Msh2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Identification and characterization of a family of mammalian methyl-CpG binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Dysregulated expression of beta-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

A clonal marker induced by mutation in mouse intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207767

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207767

1 reference

PubMed ID

15184874

Dimensions Publication ID

28 June 2017

0 references

1 reference

PubMed ID

15184874