(Q31085503)

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Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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Emanual Maverakis

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Emanual Maverakis

12

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author name string

Wenchang Guo

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ruiwu Liu

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Yoko Ono

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ai-Hong Ma

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Anthony Martinez

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Eduardo Sanchez

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Yan Wang

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wenzhe Huang

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Anisha Mazloom

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jixian Li

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jinying Ning

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Kit S Lam

13

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Hsing-Jien Kung

14

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

16 August 2012

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Europe PubMed Central

PMC publication ID

13 August 2017

Molecular Pharmacology

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Europe PubMed Central

PMC publication ID

13 August 2017

82

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

938-947

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1.

1 reference

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21 June 2018

MicroRNA-195 promotes apoptosis in mouse podocytes via enhanced caspase activity driven by BCL2 insufficiency

1 reference

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microRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting Cyclin D1 and Bcl-2.

1 reference

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miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8

1 reference

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Lipopolysaccharide-induced miR-1224 negatively regulates tumour necrosis factor-α gene expression by modulating Sp1.

1 reference

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Identification of an allosteric signaling network within Tec family kinases

1 reference

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T-cell signaling regulated by the Tec family kinase, Itk.

1 reference

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In vivo significance of ITK-SLP-76 interaction in cytokine production

1 reference

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The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma

1 reference

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1 reference

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T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

1 reference

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ATM is down-regulated by N-Myc-regulated microRNA-421.

1 reference

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T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

1 reference

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21 June 2018

The Tec family kinase Itk exists as a folded monomer in vivo

1 reference

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Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma.

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AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

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Selective targeting of ITK blocks multiple steps of HIV replication.

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Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcome

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Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

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A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation

1 reference

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21 June 2018

Solution-phase parallel synthesis of a 1,2,7-trialkyl-1H-imidazo[4,5-g]quinoxalin-6-ol library scaffold

1 reference

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Tec family kinases in T lymphocyte development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477223

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Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

1 reference

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Selective Itk inhibitors block T-cell activation and murine lung inflammation

1 reference

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Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors

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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

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Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

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A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor

1 reference

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A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library.

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Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

1 reference

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Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

1 reference

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Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

1 reference

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Identifiers

10.1124/MOL.112.079889

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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