(Q31085777)

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Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

apoptotic process

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phosphorylation

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renal cell carcinoma

1 reference

based on heuristic

inferred from title

Courtney Nicholas

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

author name string

Matthew A Bill

1

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Europe PubMed Central

PMC publication ID

19 October 2017

Thomas A Mace

3

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Europe PubMed Central

PMC publication ID

19 October 2017

Jonathan P Etter

4

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Chenglong Li

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Eric B Schwartz

6

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

James R Fuchs

7

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Gregory S Young

8

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Li Lin

9

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Jiayuh Lin

10

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Lei He

11

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Mitch Phelps

12

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Pui-Kai Li

13

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Europe PubMed Central

PMC publication ID

19 October 2017

Gregory B Lesinski

14

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Europe PubMed Central

PMC publication ID

19 October 2017

language of work or name

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publication date

10 August 2012

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Europe PubMed Central

PMC publication ID

19 October 2017

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

e40724

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

copyright license

Creative Commons Attribution 4.0 International

10 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The European Medicines Agency review of pazopanib for the treatment of advanced renal cell carcinoma: summary of the scientific assessment of the Committee for Medicinal Products for Human Use

1 reference

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1 reference

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1 reference

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1 reference

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Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways

1 reference

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21 June 2018

Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3.

1 reference

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21 June 2018

Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects.

1 reference

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The biology of myeloid‐derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity

1 reference

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A liquid chromatography–tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma

1 reference

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Targeting Stat3 in the Myeloid Compartment Drastically Improves the In vivo Antitumor Functions of Adoptively Transferred T Cells

1 reference

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21 June 2018

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

1 reference

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Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells

1 reference

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21 June 2018

Cancer statistics, 2010

1 reference

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21 June 2018

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

1 reference

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21 June 2018

Inhibition of p-STAT3 enhances IFN-alpha efficacy against metastatic melanoma in a murine model.

1 reference

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21 June 2018

Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs

1 reference

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21 June 2018

Curcumin inhibits constitutive STAT3 phosphorylation in human pancreatic cancer cell lines and downregulation of survivin/BIRC5 gene expression

1 reference

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21 June 2018

A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes

1 reference

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21 June 2018

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

1 reference

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21 June 2018

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

1 reference

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21 June 2018

Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines

1 reference

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21 June 2018

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor.

1 reference

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21 June 2018

Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells

1 reference

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21 June 2018

Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

1 reference

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IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis

1 reference

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Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice

1 reference

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Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein

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High-throughput screening fluorescence polarization assay for tumor-specific Hsp90.

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STAT3 polymorphism predicts interferon-alfa response in patients with metastatic renal cell carcinoma

1 reference

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IFN-alpha-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

1 reference

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Targeting STAT3 affects melanoma on multiple fronts

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STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells

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p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation

1 reference

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Stat proteins and oncogenesis

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1 reference

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Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

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1 reference

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A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.

1 reference

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Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign

1 reference

https://pubmed.ncbi.nlm.nih.gov/22899991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of signal transducer and activator of transcription 3 in renal cell carcinoma: a study of incidence and its association with pathological features and clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22899991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting STAT3 in cancer: how successful are we?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22899991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0040724

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

2012PLoSO...740724B

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

ResearchGate publication ID

0 references

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