(Q31105537)

28 June 2017

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title

Animal models of neurodegenerative disease: insights from in vivo imaging studies (English)

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28 June 2017

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Elissa M Strome

1

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PubMed ID

17357857

28 June 2017

Doris J Doudet

series ordinal

2

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28 June 2017

1 July 2007

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Molecular Imaging and Biology

28 June 2017

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28 June 2017

9

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28 June 2017

4

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28 June 2017

186-195

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https://scigraph.springernature.com/pub.10.1007/s11307-007-0093-4

28 June 2017

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https://api.crossref.org/works/10.1007%2FS11307-007-0093-4

GDNF protects against 6-OHDA nigrostriatal lesion: in vivo study with microdialysis and PET.

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12 December 2020

Magnetic resonance angiography and vascular corrosion casting as tools in biomedical research: application to transgenic mice modeling Alzheimer's disease

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12 December 2020

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

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12 December 2020

The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease

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12 December 2020

Magnetic resonance imaging and spectroscopy in assessing 3-nitropropionic acid-induced brain lesions: an animal model of Huntington's disease.

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12 December 2020

Brain glucose hypometabolism after perirhinal lesions in baboons: implications for Alzheimer disease and aging

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12 December 2020

Distribution kinetics of 18F-DOPA in weaver mutant mice

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12 December 2020

Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging

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12 December 2020

Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging

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12 December 2020

Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

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12 December 2020

Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease

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12 December 2020

Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease

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12 December 2020

In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD.

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12 December 2020

PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease.

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12 December 2020

In vivo PET studies of the dopamine D1 receptors in rhesus monkeys with long-term MPTP-induced Parkinsonism

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12 December 2020

Cell therapy in Parkinson's disease

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12 December 2020

Density and affinity of the dopamine D2 receptors in aged symptomatic and asymptomatic MPTP-treated monkeys: PET studies with [11C]raclopride

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12 December 2020

Bilateral increase in striatal dopamine D2 receptor density in the 6-hydroxydopamine-lesioned rat: a serial in vivo investigation with small animal PET.

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12 December 2020

Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment.

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12 December 2020

Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease

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12 December 2020

Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition.

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12 December 2020

Novel observations with FDOPA-PET imaging after early nigrostriatal damage

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12 December 2020

The validity of animal models of depression

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12 December 2020

Opiate receptor avidity is reduced bilaterally in rhesus monkeys unilaterally lesioned with MPTP.

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12 December 2020

Combined PET/MRS brain studies show dynamic and long-term physiological changes in a primate model of Parkinson disease.

1 reference

12 December 2020

Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease.

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12 December 2020

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

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12 December 2020

MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys.

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12 December 2020

6-[18F]fluoro-L-dopa and cerebral blood flow in unilaterally MPTP-treated monkeys

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12 December 2020

In vivo visualization of Alzheimer's amyloid plaques by magnetic resonance imaging in transgenic mice without a contrast agent

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12 December 2020

Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts.

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12 December 2020

Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism

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12 December 2020

Comparison of MR images and histochemical localization of intra-arterially administered microglia surrounding beta-amyloid deposits in the rat brain

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12 December 2020

Impaired eyeblink conditioning and decreased hippocampal volume in PDAPP V717F mice.

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12 December 2020

Of mice and men: more neurobiology in dementia

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12 December 2020

19F and 1H MRI detection of amyloid beta plaques in vivo

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12 December 2020

Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 11C-CFT.

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12 December 2020

"In vivo" visualization by positron emission tomography of the progressive striatal dopamine receptor damage occurring in MPTP-intoxicated non-human primates.

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12 December 2020

Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.

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12 December 2020

In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice

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12 December 2020

Effects of image resolution on autoradiographic measurements of posterior cingulate activity in PDAPP mice: implications for functional brain imaging studies of transgenic mouse models of Alzheimer's Disease

1 reference

12 December 2020

Longitudinal behavioral and 6-[18F]fluoro-L-DOPA-PET assessment in MPTP-hemiparkinsonian monkeys

1 reference

12 December 2020

6-[18F]fluoro-L-dopa uptake and [76Br]bromolisuride binding in the excitotoxically lesioned caudate-putamen of nonhuman primates studied using positron emission tomography.

1 reference

12 December 2020

Insights into Parkinson's disease models and neurotoxicity using non-invasive imaging.

1 reference

12 December 2020

Changes in extracellular space size and geometry in APP23 transgenic mice: a model of Alzheimer's disease

1 reference

12 December 2020

PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Detection of the effects of dopamine receptor supersensitivity using pharmacological MRI and correlations with PET.

1 reference

12 December 2020

Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys.

1 reference

12 December 2020

Opiate receptor avidity is reduced in non-motor impaired MPTP-lesioned rhesus monkeys.

1 reference

12 December 2020

Mapping of brain function after MPTP-induced neurotoxicity in a primate Parkinson's disease model.

1 reference

12 December 2020

In vivo PET imaging in rat of dopamine terminals reveals functional neural transplants.

1 reference

12 December 2020

Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10.

1 reference

12 December 2020

Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data.

1 reference

12 December 2020

Restricted diffusion in the brain of transgenic mice with cerebral amyloidosis

1 reference

12 December 2020

Magnetic resonance imaging to monitor pathology of caudate-putamen after excitotoxin-induced neuronal loss in the nonhuman primate brain.

1 reference

12 December 2020

MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Crossroads in GDNF therapy for Parkinson's disease

1 reference

12 December 2020

Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study

1 reference

12 December 2020

The DaNeX study of embryonic mesencephalic, dopaminergic tissue grafted to a minipig model of Parkinson's disease: preliminary findings of effect of MPTP poisoning on striatal dopaminergic markers

1 reference

12 December 2020

Uptake of 6‐[18F]fluoro‐L‐dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease

1 reference

12 December 2020

Correlation of Alzheimer-like tau hyperphosphorylation and fMRI bold intensity

1 reference

12 December 2020

3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy

1 reference

12 December 2020

Evolution of beta-amyloid induced neuropathology: magnetic resonance imaging and anatomical comparisons in the rodent hippocampus

1 reference

12 December 2020

Evaluation of the integrity of the dopamine system in a rodent model of Parkinson's disease: small animal positron emission tomography compared to behavioral assessment and autoradiography.

1 reference

12 December 2020

Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons

1 reference

12 December 2020

Noninvasive in vivo MRI detection of neuritic plaques associated with iron in APP[V717I] transgenic mice, a model for Alzheimer's disease.

1 reference

12 December 2020

Differential recovery of volitional motor function, lateralized cognitive function, dopamine agonist-induced rotation and dopaminergic parameters in monkeys made hemi-parkinsonian by intracarotid MPTP infusion.

1 reference

12 December 2020

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

12 December 2020

Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa

1 reference

12 December 2020

Tremor is associated with PET measures of nigrostriatal dopamine function in MPTP-lesioned monkeys

1 reference

12 December 2020

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

12 December 2020

Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism

1 reference

12 December 2020

MPTP-Induced pallidal lesions in rhesus monkeys.

1 reference

12 December 2020

Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.

1 reference

12 December 2020

Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats

1 reference

12 December 2020

Adenosine A2A receptor imaging with [11C]KF18446 PET in the rat brain after quinolinic acid lesion: comparison with the dopamine receptor imaging

1 reference

12 December 2020

Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease

1 reference

12 December 2020

Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease.

1 reference

12 December 2020

Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease

1 reference

12 December 2020

Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number

1 reference

12 December 2020

Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging.

1 reference

12 December 2020

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

1 reference

12 December 2020

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

1 reference

12 December 2020

Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation

1 reference

12 December 2020

6-[18F]Fluoro-L-DOPA PET studies of the turnover of dopamine in MPTP-induced parkinsonism in monkeys.

1 reference

12 December 2020

Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.

1 reference

12 December 2020

Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo.

1 reference

12 December 2020

PET studies of functional compensation in a primate model of Parkinson's disease

1 reference

12 December 2020

Imaging and Therapeutics The Role of Neuronal Transport in the Regional Specificity of L-DOPA Accumulation in Brain

1 reference

12 December 2020

PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates.

1 reference

12 December 2020

Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile

1 reference

12 December 2020

6-18F-L-dopa imaging of the dopamine neostriatal system in normal and clinically normal MPTP-treated rhesus monkeys

1 reference

12 December 2020

Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice

1 reference

12 December 2020

Characterization and localization of the Huntington disease gene product

1 reference

12 December 2020

Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice.

1 reference

12 December 2020

Effect of L-dopa and 6-hydroxydopamine lesioning on [11C]raclopride binding in rat striatum, quantified using PET

1 reference

12 December 2020

Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs.

1 reference

12 December 2020

Amyloid imaging in aged and young macaques with [11C]PIB and [18F]FDDNP.

1 reference

12 December 2020

10.1007/S11307-007-0093-4

Identifiers

DOI

1 reference

PubMed ID

17357857

Dimensions Publication ID

28 June 2017

0 references

1 reference

PubMed ID

17357857