(Q31002507)

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Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 June 2017

Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease (English)

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Europe PubMed Central

PubMed publication ID

28 June 2017

Huntington's disease

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Alpaslan Dedeoglu

object named as

Alpaslan Dedeoglu

3

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Ole A. Andreassen

object named as

Ole A Andreassen

2

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Michael R. Hayden

object named as

Michael Hayden

5

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Blair R Leavitt

4

object named as

Blair Leavitt

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Europe PubMed Central

PubMed publication ID

28 June 2017

Christopher A Ross

7

object named as

Christopher A Ross

1 reference

Europe PubMed Central

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28 June 2017

Robert J Ferrante

8

object named as

Robert J Ferrante

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Europe PubMed Central

PubMed publication ID

28 June 2017

9

object named as

M Flint Beal

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

David R Borchelt

6

object named as

David Borchelt

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Europe PubMed Central

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28 June 2017

author name string

Bruce G Jenkins

1

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28 June 2017

language of work or name

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publication date

31 August 2005

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Europe PubMed Central

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28 June 2017

Journal of Neurochemistry

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Europe PubMed Central

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28 June 2017

95

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Europe PubMed Central

PubMed publication ID

28 June 2017

2

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Europe PubMed Central

PubMed publication ID

28 June 2017

553-562

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Europe PubMed Central

PubMed publication ID

28 June 2017

describes a project that uses

NMR spectroscopy

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Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Decreased brain N-acetylaspartate in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Trinucleotide repeats and neurodegenerative disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Relationship between trinucleotide repeats and neuropathological changes in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Regulation of mammalian brain cell volume

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

CAG-polyglutamine-repeat mutations: independence from gene context

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

CAG repeat number governs the development rate of pathology in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Clinical correlation of striatal 1H MRS changes in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Metabolic changes in quinolinic acid-lesioned rat striatum detected non-invasively by in vivo (1)H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03411.X

21 January 2018

Identifiers

10.1111/J.1471-4159.2005.03411.X

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

ResearchGate publication ID

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