(Q31135843)

14 October 2017

4 references

14 March 2019

21 March 2019

25 April 2019

19 November 2019

Evidence of a vicious cycle in glutamine synthesis and breakdown in pathogenesis of hepatic encephalopathy-therapeutic perspectives (English)

1 reference

14 October 2017

hepatic encephalopathy

4 references

14 March 2019

21 March 2019

25 April 2019

19 November 2019

1 reference

19 November 2019

1

Milan Holecek

1 reference

14 October 2017

31 August 2013

1 reference

14 October 2017

1 March 2014

4 references

14 March 2019

21 March 2019

25 April 2019

19 November 2019

Metabolic Brain Disease

5 references

14 October 2017

14 March 2019

21 March 2019

25 April 2019

19 November 2019

29

1 reference

14 October 2017

1

1 reference

14 October 2017

9-17

1 reference

Creative Commons Attribution-NonCommercial 2.0 Generic

14 October 2017

start time

31 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s11011-013-9428-9

0 references

cites work

Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Safety of ornithine phenylacetate in cirrhotic decompensated patients: an open-label, dose-escalating, single-cohort study.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Oral branched-chain amino acids have a beneficial effect on manifestations of hepatic encephalopathy in a systematic review with meta-analyses of randomized controlled trials.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Glutamine supplementation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Neuroinflammation in acute liver failure: mechanisms and novel therapeutic targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Pharmacology and safety of glycerol phenylbutyrate in healthy adults and adults with cirrhosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Ammonia toxicity and its prevention in inherited defects of the urea cycle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Identifying the direct effects of ammonia on the brain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Exogenous glutamine--compensating a shortage?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Mechanisms of ammonia-induced astrocyte swelling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Minimal hepatic encephalopathy: diagnosis, clinical significance and recommendations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Intestinal glutaminase activity is increased in liver cirrhosis and correlates with minimal hepatic encephalopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Non-absorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Renal metabolism of amino acids: its role in interorgan amino acid exchange

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

The effect of induced hyperammonemia on renal ammonia metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Branched-chain amino acids for hepatic encephalopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

21 June 2018

Neurobiology of ammonia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Glutamine synthetase in brain: effect of ammonia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Activation of system L heterodimeric amino acid exchangers by intracellular substrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Splanchnic and leg exchange of amino acids and ammonia in acute liver failure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Compartmentation of brain glutamate metabolism in neurons and glia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Role of glutamine in human carbohydrate metabolism in kidney and other tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

The contribution of various organs to ammonia formation: a review of factors determining the arterial ammonia concentration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

alpha-Ketoglutarate application in hemodialysis patients improves amino acid metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Plasma and erythrocyte amino acid levels in normal adult subjects fed a high protein meal with and without added monosodium glutamate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Eckʼs Fistula Encephalopathy in Germfree Dogs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Origin and possible significance of alanine production by skeletal muscle.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

The formation of glutamine and alanine in skeletal muscle.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

False neurotransmitters and hepatic failure.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Severe cerebral damage in ornithine transcarbamylase deficiency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

21 June 2018

Gut glutamine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Phenylacetylglutamine May Replace Urea as a Vehicle for Waste Nitrogen Excretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Dietary modulation of small intestinal glutamine transport in intestinal brush border membrane vesicles of rats.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Body cell mass and leucine metabolism in cirrhosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Effect of portacaval anastomosis on glutamine synthetase activities in liver, brain, and skeletal muscle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

The effect of normalization of plasma amino acids on hepatic encephalopathy in man

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Medical treatment of hyperammoniemia in the elderly. Controlled clinical study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Anti-ammonemic activity of the gamma-ethyl ester of glutamic acid. Controlled clinical study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Metabolism of [13N]ammonia in rat lung

21 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Survival after treatment with phenylacetate and benzoate for urea-cycle disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Can glutamine enable the critically ill to cope better with infection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

L-Ornithine phenylacetate (OP): a novel treatment for hyperammonemia and hepatic encephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

DNA microarray analysis identified molecular pathways mediating the effects of supplementation of branched-chain amino acids on CCl4-induced cirrhosis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Blood—Brain Barrier to Ammonia in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Stimulation of muscle ammonia production during exercise following branched-chain amino acid supplementation in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Oral glutamine challenge in cirrhotics pre- and post-liver transplantation: a psychometric and analyzed EEG study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Effect of alternative pathway therapy on branched chain amino acid metabolism in urea cycle disorder patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-013-9428-9

Brain microvessels take up large neutral amino acids in exchange for glutamine. Cooperative role of Na+-dependent and Na+-independent systems.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3930847

Plasma amino acid levels after carbon tetrachloride induced acute liver damage. A dose-response and time-response study in rats

25 November 2018

1 reference

12 December 2020

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

1 reference

12 December 2020

Tubular handling of amino acids after intravenous infusion of amino acids in healthy humans

1 reference

12 December 2020

Plasma alpha-ketoglutarate in urea cycle enzymopathies and its role as a harbinger of hyperammonemic coma

1 reference

12 December 2020

Hyperammonemia-induced depletion of glutamate and branched-chain amino acids in muscle and plasma

1 reference

12 December 2020

Effects of monosodium glutamate supplementation on glutamine metabolism in adult rats

1 reference

12 December 2020

Ornicetil on encephalopathy. Effect of ornicetil (ornithine alpha-ketoglutarate) on encephalopathy in patients with acute and chronic liver disease

1 reference

12 December 2020

Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. Quantitative importance of glutamine, glutamate, and aspartate

1 reference

12 December 2020

Plasma amino acids in four models of experimental liver injury in rats

1 reference

12 December 2020

Glutamine and smooth muscle morphology of the gut in rats on total parenteral nutrition

1 reference

12 December 2020

Plasma amino acid patterns in hepatic encephalopathy of differing etiology

1 reference

12 December 2020

Leucine metabolism in rats with cirrhosis

1 reference

12 December 2020

Circadian variations in plasma and erythrocyte glutamate concentrations in adult men consuming a diet with and without added monosodium glutamate

1 reference

12 December 2020

Plasma glutamine concentration: A guide in the management of urea cycle disorders

1 reference

12 December 2020

The effect of glutamic acid on the coma of hepatic failure

1 reference

12 December 2020

Abnormal phenylalanine hydroxylation and tyrosine oxidation in a patient with acute fulminant liver disease with correction by liver transplantation

1 reference

12 December 2020

Regulation of renal ammoniagenesis in the dog with chronic metabolic acidosis: effect of a glutamine load

1 reference

12 December 2020

Effect of hyperammonemia on leucine and protein metabolism in rats

1 reference

12 December 2020

Treatment of hepatic coma with L-glutamic acid

1 reference

12 December 2020

10.1007/S11011-013-9428-9

Identifiers

DOI

1 reference

Dimensions Publication ID

14 October 2017

0 references

1 reference

14 October 2017

PubMed publication ID

23996300

1 reference