(Q31147725)

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Integration of Global Analyses of Host Molecular Responses with Clinical Data To Evaluate Pathogenesis and Advance Therapies for Emerging and Re-emerging Viral Infections

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 June 2017

1 reference

Europe PubMed Central

Integration of Global Analyses of Host Molecular Responses with Clinical Data To Evaluate Pathogenesis and Advance Therapies for Emerging and Re-emerging Viral Infections (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Jason Kindrachuk

3

object named as

Jason Kindrachuk

0 references

Daniel S Chertow

2

object named as

Daniel S Chertow

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

author name string

Shane D Falcinelli

1

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Jason Kindrachuk

3

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

publication date

5 August 2016

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

ACS Infectious Diseases

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

787-799

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Protein kinases--the major drug targets of the twenty-first century?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Comparison of the Chicken and Turkey Proteomes and Phosphoproteomes in the Development of Poultry-Specific Immuno-Metabolism Kinome Peptide Arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An outbreak of coronavirus OC43 respiratory infection in Normandy, France

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systematic approach for analysis of peptide array kinome data

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stunned silence: gene expression programs in human cells infected with monkeypox or vaccinia virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human asymptomatic Ebola infection and strong inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic Phosphorylation of VP30 Is Essential for Ebola Virus Life Cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of host cell gene expression in cowpox, monkeypox or vaccinia virus-infected cells reveals virus-specific regulation of immune response genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein kinase complement of the human genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide arrays for kinome analysis: new opportunities and remaining challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing the contribution of interferon antagonism to the virulence of West African Ebola viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Family cluster of Middle East respiratory syndrome coronavirus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory responses in Ebola virus-infected patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical analysis of protein kinase specificity determinants

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tale of two clades: monkeypox viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of Middle East respiratory syndrome coronavirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling--2000 and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early immune responses accompanying human asymptomatic Ebola infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of swine as a host for the Reston ebolavirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coronavirus infections in hospitalized pediatric patients with acute respiratory tract disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine modulation correlates with severity of monkeypox disease in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human coronavirus OC43 causes influenza-like illness in residents and staff of aged-care facilities in Melbourne, Australia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of yeast protein kinases using protein chips.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational Analysis of the Predicted Evolutionary Conservation of Human Phosphorylation Sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical manifestations of human monkeypox influenced by route of infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new antibiotic and the evolution of resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ebola and marburg hemorrhagic fever

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Status of human monkeypox: clinical disease, epidemiology and research

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral replication and host gene expression in alveolar macrophages infected with Ebola virus (Zaire strain)

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the host response to pichinde virus infection in the Syrian golden hamster by species-specific kinome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variola and monkeypox viruses utilize conserved mechanisms of virion motility and release that depend on abl and SRC family tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIIKA 2: an expanded, web-based platform for analysis of kinome microarray data

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrum of clinical illness in hospitalized patients with "common cold" virus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical features and pathobiology of Ebolavirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus: a case-control study of hospitalized patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NCATS launches drug repurposing program

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection with MERS-CoV causes lethal pneumonia in the common marmoset

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation status of the phosphoprotein P of rinderpest virus modulates transcription and replication of the genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The druggable genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural phosphoprotein M2-1 of the human respiratory syncytial virus is an RNA binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Monkeypox

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systems kinomics demonstrates Congo Basin monkeypox virus infection selectively modulates host cell signaling responses as compared to West African monkeypox virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global trends in emerging infectious diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Management of Ebola Virus Disease in the United States and Europe

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunopathogenesis of severe acute respiratory disease in Zaire ebolavirus-infected pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virulence and pathophysiology of the Congo Basin and West African strains of monkeypox virus in non-human primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reston ebolavirus in humans and animals in the Philippines: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/ACSINFECDIS.6B00104

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

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