(Q31627070)

3 July 2017

title

The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner (English)

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3 July 2017

Ye R

1

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3 July 2017

Bodero A

2

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3 July 2017

Zhou BB

3

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3 July 2017

Khanna KK

4

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3 July 2017

Lavin MF

5

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3 July 2017

Lees-Miller SP

6

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3 July 2017

language of work or name

English

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publication date

28 November 2000

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Journal of Biological Chemistry

3 July 2017

published in

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3 July 2017

volume

276

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3 July 2017

issue

7

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3 July 2017

page(s)

4828-4833

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Dietary phytoestrogens and cancer: in vitro and in vivo studies

3 July 2017

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Neonatal genistein chemoprevents mammary cancer.

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Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II.

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Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

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Caspases: killer proteases

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

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Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

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ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

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Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

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DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

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DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45

21 January 2018

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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

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Caffeine inhibits the checkpoint kinase ATM

21 January 2018

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The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

21 January 2018

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A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

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Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

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Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

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Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004894200

21 January 2018

1 reference

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The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

21 January 2018

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Tyrosine kinase inhibition affects type 1 angiotensin II receptor internalization

21 January 2018

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The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta

21 January 2018

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Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M004894200

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3 July 2017

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