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Cleavage and inactivation of ATM during apoptosis.
scientific article
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scholarly article
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
title
Cleavage and inactivation of ATM during apoptosis
(English)
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stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
main subject
apoptotic process
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inferred from title
author
Stephen P Jackson
series ordinal
4
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
Fabrizio Daddadifagagna
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
author name string
G C Smith
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1
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
N D Lakin
series ordinal
3
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
language of work or name
English
0 references
publication date
1 September 1999
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
volume
19
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
issue
9
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Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
page(s)
6076-6084
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stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
cites work
ATM: from gene to function
1 reference
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PubMed Central
reference URL
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6 September 2017
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
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PubMed Central
reference URL
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6 September 2017
Enhanced phosphorylation of p53 by ATM in response to DNA damage
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6 September 2017
Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
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PubMed Central
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6 September 2017
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
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6 September 2017
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
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6 September 2017
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
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6 September 2017
DNA damage induces phosphorylation of the amino terminus of p53
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6 September 2017
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
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PubMed Central
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6 September 2017
Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells
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6 September 2017
The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage
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6 September 2017
Programmed cell death in animal development
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6 September 2017
Atm-deficient mice: a paradigm of ataxia telangiectasia
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6 September 2017
DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis
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6 September 2017
cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
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6 September 2017
Toward an understanding of the molecular mechanisms of physiological cell death.
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6 September 2017
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
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6 September 2017
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
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6 September 2017
Apoptosis in the pathogenesis and treatment of disease
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6 September 2017
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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6 September 2017
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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6 September 2017
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
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6 September 2017
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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6 September 2017
Mechanisms and Functions of Cell Death
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6 September 2017
Apoptosis: Mechanisms and Roles in Pathology
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6 September 2017
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
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6 September 2017
ATM-related genes: what do they tell us about functions of the human gene?
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14 September 2017
Protease activation during apoptosis: death by a thousand cuts?
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14 September 2017
Evidence for a G2 checkpoint in p53-independent apoptosis induction by X-irradiation
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14 September 2017
Ataxia-telangiectasia: closer to unraveling the mystery
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14 September 2017
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
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27 September 2017
Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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27 September 2017
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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27 September 2017
DNA damage detection by DNA dependent protein kinase and related enzymes.
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27 September 2017
Cancer predisposition. Ataxia-telangiectasia at the crossroads
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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27 September 2017
Ataxia-telangiectasia and cellular responses to DNA damage.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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27 September 2017
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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27 September 2017
DNA repair: PARP - another guardian angel?
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23 June 2018
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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23 June 2018
Caspases: intracellular signaling by proteolysis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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23 June 2018
Death substrates come alive
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
retrieved
23 June 2018
Analysis of the ATM protein in wild-type and ataxia telangiectasia cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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23 June 2018
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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23 June 2018
Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
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23 June 2018
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
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PubMed Central
reference URL
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23 June 2018
Dual roles of ATM in the cellular response to radiation and in cell growth control.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84521
retrieved
31 August 2018
Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10454555
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10454555
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The product of the ATM gene is a 370-kDa nuclear phosphoprotein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10454555
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Substrate specificities of caspase family proteases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10454555
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Proteases to die for
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10454555
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.9.6076
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
PMC publication ID
84521
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
PubMed publication ID
10454555
1 reference
stated in
Europe PubMed Central
PMC publication ID
84521
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 December 2019
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