(Q31645732)

3 July 2017

title

Polymerization of plasminogen activator inhibitor-1. (English)

1 reference

ORCID Public Data File 2021

3 July 2017

1 reference

1 reference

author name string

Zhou A

1

1 reference

3 July 2017

Faint R

2

1 reference

3 July 2017

Charlton P

3

1 reference

3 July 2017

Dafforn TR

4

1 reference

3 July 2017

Carrell RW

5

1 reference

3 July 2017

Lomas DA

6

1 reference

3 July 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

Journal of Biological Chemistry

3 July 2017

published in

1 reference

3 July 2017

volume

276

1 reference

3 July 2017

issue

12

1 reference

3 July 2017

page(s)

9115-9122

1 reference

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

3 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Purification of active human plasminogen activator inhibitor 1 from Escherichia coli. Comparison with natural and recombinant forms purified from eucaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Mapping the serpin-proteinase complex using single cysteine variants of alpha1-proteinase inhibitor Pittsburgh

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Structural basis of latency in plasminogen activator inhibitor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Latent alpha1-antichymotrypsin. A molecular explanation for the inactivation of alpha1-antichymotrypsin in chronic bronchitis and emphysema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Biological implications of a 3 A structure of dimeric antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

A 2.6 A structure of a serpin polymer and implications for conformational disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Cleaved antitrypsin polymers at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Heteropolymerization of S, I, and Z alpha1-antitrypsin and liver cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Antithrombin-TRI (Ala382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

COOH-terminal substitutions in the serpin C1 inhibitor that cause loop overinsertion and subsequent multimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Plasminogen-activator inhibitor type 2 (PAI-2) is a spontaneously polymerising SERPIN. Biochemical characterisation of the recombinant intracellular and extracellular forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Functional effects of single amino acid substitutions in the region of Phe113 to Asp138 in the plasminogen activator inhibitor 1 molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Multiphasic zone electrophoresis, IV. Design and analysis of discontinuous buffer systems with a digital computer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Identification of the binding site for a low-molecular-weight inhibitor of plasminogen activator inhibitor type 1 by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Purification and characterization of active and stable recombinant plasminogen-activator inhibitor accumulated at high levels in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

The acid stabilization of plasminogen activator inhibitor-1 depends on protonation of a single group that affects loop insertion into beta-sheet A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

A Kinetic Mechanism for the Polymerization of α1-Antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Pathogenic α1-Antitrypsin Polymers Are Formed by Reactive Loop-β-Sheet A Linkage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Crystallization and Preliminary X-ray Diffraction Analysis of Two Conformations of Intact Human Antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Preparation and characterization of latent alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Structural explanation for the deficiency of S alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Formation and properties of C1-inhibitor polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Bovine endothelial cell plasminogen activator inhibitor. Purification and heat activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

Kinetically controlled folding of the serpin plasminogen activator inhibitor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010631200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010631200

1 reference

3 July 2017

1 reference