(Q31858938)

4 July 2017

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title

DNA damage: Chk1 and Cdc25, more than meets the eye. (English)

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4 July 2017

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N C Walworth

1

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4 July 2017

language of work or name

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1 February 2001

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Current Opinion in Genetics & Development

4 July 2017

published in

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4 July 2017

volume

11

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4 July 2017

issue

1

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4 July 2017

page(s)

78-82

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Universal control mechanism regulating onset of M-phase

4 July 2017

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Cyclin-dependent kinases: engines, clocks, and microprocessors

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cdc25+ functions as an inducer in the mitotic control of fission yeast.

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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

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7 January 2021

Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells

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mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.

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7 January 2021

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

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7 January 2021

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

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7 January 2021

Sensing and responding to DNA damage.

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7 January 2021

The G2-phase DNA-damage checkpoint

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7 January 2021

Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9

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7 January 2021

A novel Rad24 checkpoint protein complex closely related to replication factor C.

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7 January 2021

A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins

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7 January 2021

Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

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Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

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Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

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7 January 2021

14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast

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7 January 2021

Meiotic DNA replication checkpoint control in fission yeast

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7 January 2021

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

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7 January 2021

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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7 January 2021

14-3-3 proteins act as negative regulators of the mitotic inducer Cdc25 in Xenopus egg extracts

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7 January 2021

The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts

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7 January 2021

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

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7 January 2021

DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

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7 January 2021

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

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7 January 2021

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

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7 January 2021

Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

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7 January 2021

Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25.

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7 January 2021

Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site

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7 January 2021

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

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7 January 2021

Substrate specificity determinants of the checkpoint protein kinase Chk1

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7 January 2021

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

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7 January 2021

Regulation of mitotic inhibitor Mik1 helps to enforce the DNA damage checkpoint

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7 January 2021

Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis

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7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

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7 January 2021

Chromosome cohesion, condensation, and separation

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7 January 2021

Polo-like kinase-1 is a target of the DNA damage checkpoint

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7 January 2021

Rapid destruction of human Cdc25A in response to DNA damage

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7 January 2021

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

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7 January 2021

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

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7 January 2021

Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

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7 January 2021

Activation of the DNA replication checkpoint through RNA synthesis by primase

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7 January 2021

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

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7 January 2021

10.1016/S0959-437X(00)00160-X

Identifiers

DOI

1 reference

4 July 2017

1 reference