(Q31875103)

4 July 2017

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title

Crucial role of cytokines in sex steroid formation in normal and tumoral tissues (English)

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4 July 2017

1

Simard J

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4 July 2017

Gingras S

2

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4 July 2017

publication date

1 January 2001

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Molecular and Cellular Endocrinology

4 July 2017

published in

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4 July 2017

volume

171

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4 July 2017

issue

1-2

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4 July 2017

page(s)

25-40

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Steroidal regulation of oestradiol-17 beta dehydrogenase activity of the human breast cancer cell line MCF-7

4 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Effects of human breast fibroblasts on growth and 17 beta-estradiol dehydrogenase activity of MCF-7 cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Paracrine influence of human breast stromal fibroblasts on breast epithelial cells: secretion of a polypeptide which stimulates reductive 17 beta-oestradiol dehydrogenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin 6 is secreted by breast fibroblasts and stimulates 17 beta-oestradiol oxidoreductase activity of MCF-7 cells: possible paracrine regulation of breast 17 beta-oestradiol levels

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Steroid hormone receptors in human colon cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Cytokine gene expression during the elicitation phase of contact sensitivity: regulation by endogenous IL-4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-alpha and interleukin-4 predicts improved survival

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Endogenous hormones and breast cancer risk

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin-6 inhibits the potent stimulatory action of androgens, glucocorticoids and interleukin-1 alpha on apolipoprotein D and GCDFP-15 expression in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Potent stimulatory effect of interleukin-1 alpha on apolipoprotein D and gross cystic disease fluid protein-15 expression in human breast-cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Growth-independent induction of spermidine transport by IL-4 and IL-13 in ZR-75-1 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The relationship between 17 beta-hydroxysteroid dehydrogenase activity and oestrogen concentrations in human breast tumours and in normal breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Fadrozole HCL (CGS-16949A) versus megestrol acetate treatment of postmenopausal patients with metastatic breast carcinoma: results of two randomized double blind controlled multiinstitutional trials

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

STATs and gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Localization of IL-4 and IL-4 receptors in the human term placenta, decidua and amniochorionic membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Expression and localization of the Th2-type cytokine interleukin-13 and its receptor in the placenta during human pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin-13 stimulates interleukin-6 production by human keratinocytes. Similarity with interleukin-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Expression and function of members of the cytokine receptor superfamily on breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Biologic activity of dehydroepiandrosterone sulfate in man

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The interaction of cytokines in regulating oestradiol 17 beta-hydroxysteroid dehydrogenase activity in MCF-7 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Postmenopausal hormone use and risk for colorectal cancer and adenoma

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Correlation of in vivo and in vitro activities of some naturally occurring androgens using a radioreceptor assay for 5alpha-dihydrotestosterone with rat prostate cytosol receptor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The effect of sex hormones and tamoxifen on the growth of human gastric and colorectal cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Immunolocalisation of interleukin-4 and interleukin-4 receptor in placenta and fetal membranes in association with pre-term labour and pre-eclampsia

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

An interleukin-4-induced transcription factor: IL-4 Stat

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

STATs: signal transducers and activators of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Human keratinocytes constitutively express IL-4 receptor molecules and respond to IL-4 with an increase in B7/BB1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin-4 receptor and epidermal growth factor receptor expression in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Loss of interleukin 4 receptor-associated molecule gp200-MR6 in human breast cancer: prognostic significance

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Macrophages in human breast disease: a quantitative immunohistochemical study

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL4 sharing a DNA binding motif with an interferon-gamma-induced nuclear binding factor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1)

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

1 reference

7 January 2021

The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Regulation of STAT-dependent pathways by growth factors and cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Jaks and STATs: biological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(a)anthracene (DMBA) in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Expression and Characterization of Recombinant Type 2 3 -Hydroxysteroid Dehydrogenase (HSD) from Human Prostate: Demonstration of Bifunctional 3 /17 -HSD Activity and Cellular Distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Human 3 beta-hydroxysteroid dehydrogenase/delta 5----4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Human tumour-associated NK cells secrete increased amounts of interferon-gamma and interleukin-4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Full length cDNA structure and deduced amino acid sequence of human 3 beta-hydroxy-5-ene steroid dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Widespread tissue distribution of steroid sulfatase, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD), 17 beta-HSD 5 alpha-reductase and aromatase activities in the rhesus monkey

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Distribution of 17 beta-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The regulation of 3 beta-hydroxysteroid dehydrogenase expression

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

A comparison of the in vivo uptake and metabolism of 3H-oestrone and 3H-oestradiol by normal breast and breast tumour tissues in post-menopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Inhibition of 1,2-dimethylhydrazine-induced colon tumorigenesis in Balb/c mice by dehydroepiandrosterone.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Importance of estrogen sulfates in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Sebaceous gland response in man to the administration of testosterone, delta-4-androstenedione, and dehydroisoandrosterone

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Down-regulation of estrogen receptors by androgens in the ZR-75-1 human breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Progestin induction of 17 beta-hydroxysteroid dehydrogenase enzyme protein in the T-47D human breast-cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Testosterone, dihydrotestosterone and oestradiol levels in postmenopausal breast cancer tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Breast cancer and the role of cytokines in regulating estrogen synthesis: an emerging hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Congenital adrenal hyperplasia due to point mutations in the type II 3 beta-hydroxysteroid dehydrogenase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The estrogenic and antiestrogenic activities of androgens in female target tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Estrogenic effects of 5-androstene-3 beta, 17 beta-diol at physiological concentrations and its possible implication in the etiology of breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Molecular basis of congenital adrenal hyperplasia due to 3 beta- hydroxysteroid dehydrogenase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Cytochromes P450 11: expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

The Relationship Between the In Vitro Activity of 3β-Hydroxysteroid Dehydrogenase Δ4–5-Isomerase in Human Sebaceous Glands and Their Secretory Activity In Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Multiple forms of 17 beta-hydroxysteroid oxidoreductase in human breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

STAT6: its role in interleukin 4-mediated biological functions

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Decreased adherence of interleukin 6-treated breast carcinoma cells can lead to separation from neighbors after mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Steroids in normal and neoplastic breast tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Androgen metabolism in the skin of hirsute women

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Antiproliferative effect of human interleukin-4 in human cancer cell lines: studies on the mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Regulation of sex steroid formation by interleukin-4 and interleukin-6 in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Aromatase, 17 beta-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Molecular study of sex steroid receptor gene expression in human colon and in colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Flow cytometric analysis of tumour infiltrating lymphocytes in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

A and B forms of the androgen receptor are expressed in a variety of human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Estrogen receptor-mediated direct stimulation of colon cancer cell growth in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin 4-induced proliferation in normal human keratinocytes is associated with c-myc gene expression and inhibited by genistein

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Interleukin 13 elicits a subset of the activities of its close relative interleukin 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2800%2900387-7

7 January 2021

10.1016/S0303-7207(00)00387-7

Identifiers

DOI

1 reference

4 July 2017

1 reference