(Q31929689)

5 July 2017

title

Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade (English)

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5 July 2017

G Bain

1

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5 July 2017

C B Cravatt

2

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5 July 2017

C Loomans

3

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5 July 2017

J Alberola-Ila

4

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5 July 2017

S M Hedrick

5

1 reference

5 July 2017

C Murre

6

1 reference

5 July 2017

language of work or name

English

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publication date

1 February 2001

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5 July 2017

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5 July 2017

volume

2

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5 July 2017

issue

2

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5 July 2017

page(s)

165-171

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Structure and function of helix-loop-helix proteins

5 July 2017

cites work

1 reference

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

21 January 2018

1 reference

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

21 January 2018

1 reference

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

21 January 2018

1 reference

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

21 January 2018

1 reference

The helix-loop-helix gene E2A is required for B cell formation

21 January 2018

1 reference

E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas

21 January 2018

1 reference

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

21 January 2018

1 reference

Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47

21 January 2018

1 reference

High Incidence of T-Cell Tumors in E2A-Null Mice and E2A/Id1 Double-Knockout Mice

21 January 2018

1 reference

Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas

21 January 2018

1 reference

Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells

21 January 2018

1 reference

Transcription factors in hematopoiesis

21 January 2018

1 reference

Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene

21 January 2018

1 reference

Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.

21 January 2018

1 reference

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

21 January 2018

1 reference

Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

21 January 2018

1 reference

Positive selection of thymocytes

21 January 2018

1 reference

Essential role for ZAP-70 in both positive and negative selection of thymocytes

21 January 2018

1 reference

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

21 January 2018

1 reference

Protein tyrosine kinases in thymocyte development

21 January 2018

1 reference

Differential signaling by lymphocyte antigen receptors.

21 January 2018

1 reference

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

21 January 2018

1 reference

ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking

21 January 2018

1 reference

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes

21 January 2018

1 reference

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

21 January 2018

1 reference

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

1 reference

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 January 2018

1 reference

Selective requirement for MAP kinase activation in thymocyte differentiation

21 January 2018

1 reference

Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

1 reference

The Influence of the MAPK Pathway on T Cell Lineage Commitment

21 January 2018

1 reference

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

Positive and negative selection invoke distinct signaling pathways.

21 January 2018

1 reference

Induction of the early growth response (Egr) family of transcription factors during thymic selection

21 January 2018

1 reference

Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).

21 January 2018

1 reference

Multiple pituitary and ovarian defects in Krox-24 (NGFI-A, Egr-1)-targeted mice

21 January 2018

1 reference

Thymic tumorigenesis induced by overexpression of p56lck

21 January 2018

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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

21 January 2018

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Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

21 January 2018

1 reference

Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

1 reference

Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cells

21 January 2018

1 reference

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

1 reference

E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins

21 January 2018

1 reference

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

21 January 2018

1 reference

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/84273

1 reference

5 July 2017

1 reference