(Q41587202)

4 October 2017

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title

Protein tyrosine kinases in thymocyte development (English)

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4 October 2017

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A M Cheng

1

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4 October 2017

A C Chan

series ordinal

2

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4 October 2017

publication date

1 August 1997

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Current Opinion in Immunology

4 October 2017

published in

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4 October 2017

volume

9

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4 October 2017

issue

4

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4 October 2017

page(s)

528-533

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Functions of TCR and pre-TCR subunits: lessons from gene ablation

4 October 2017

cites work

1 reference

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7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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7 January 2021

Regulation of antigen receptor signal transduction by protein tyrosine kinases

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7 January 2021

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

1 reference

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7 January 2021

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1 reference

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7 January 2021

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

1 reference

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7 January 2021

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

1 reference

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7 January 2021

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

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7 January 2021

Helper T-cell development in the absence of CD4-p56 Ick association

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7 January 2021

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

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7 January 2021

Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.

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7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

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7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

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7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

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7 January 2021

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

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7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

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7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

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7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

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7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

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7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

1 reference

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7 January 2021

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

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7 January 2021

1 reference

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7 January 2021

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Profound block in thymocyte development in mice lacking p56lck

1 reference

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7 January 2021

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

1 reference

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7 January 2021

Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

1 reference

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7 January 2021

Fyn can partially substitute for Lck in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn).

1 reference

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

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7 January 2021

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

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7 January 2021

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

1 reference

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7 January 2021

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

1 reference

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7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

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7 January 2021

Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Regulation of thymocyte development through CD3: functional dissociation between p56lck and CD3 sigma in early thymic selection.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Positive and negative selection invoke distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Requirement for tyrosine kinase p56lck for thymic development of transgenic gamma delta T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

Differential contribution of Lck and Fyn protein tyrosine kinases to intraepithelial lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980106-9

7 January 2021

10.1016/S0952-7915(97)80106-9

Identifiers

DOI

1 reference

4 October 2017

1 reference