(Q32064880)

English

Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9575206%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9575206%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Cryptococcus neoforman

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based on heuristic

inferred from title

1

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11 November 2019

Jeffrey I. Gordon

7

object named as

J I Gordon

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11 November 2019

author name string

E Jackson-Machelski

2

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11 November 2019

M Higgins

3

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11 November 2019

C A McWherter

4

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11 November 2019

J A Sikorski

5

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11 November 2019

B Devadas

6

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11 November 2019

language of work or name

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publication date

1 May 1998

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11 November 2019

Journal of Biological Chemistry

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11 November 2019

273

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11 November 2019

12482-12491

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11 November 2019

20

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11 November 2019

A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. National Institute of Allergy and Infectious Diseases Mycoses Study Group and AIDS Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the alpha-mating type

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Calcineurin is required for virulence of Cryptococcus neoformans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Cloning, expression and characterization of thymidylate synthase from Cryptococcus neoformans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Cloning, sequence analysis and expression of the gene encoding imidazole glycerol phosphate dehydratase in Cryptococcus neoformans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Structure of the ubiquitin-encoding genes of Cryptococcus neoformans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Understanding covalent modifications of proteins by lipids: where cell biology and biophysics mingle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Crystal structure of the anti-fungal target N-myristoyl transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifung

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: protein N-myristoyltransferase: a new approach to antifungal therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Genetic studies reveal that myristoylCoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Biochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

The Cryptococcus neoformans GAL7 gene and its use as an inducible promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Novel biologically active nonpeptidic inhibitors of myristoylCoA:protein N-myristoyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Titration calorimetric analysis of AcylCoA recognition by myristoylCoA:protein N-myristoyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Mutational analysis of Saccharomyces cerevisiae ARF1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.20.12482

21 January 2018

Identifiers

10.1074/JBC.273.20.12482

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9575206%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

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11 November 2019

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