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Towards an understanding of somatic hypermutation
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Towards an understanding of somatic hypermutation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
author name string
Jacobs H
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
Bross L
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
publication date
1 April 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
volume
13
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
page(s)
208-218
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stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
cites work
Specificity in V(D)J recombination: new lessons from biochemistry and genetics
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VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE
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Variability in the Lambda Light Chain Sequences of Mouse Antibody
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The molecular basis of somatic hypermutation of immunoglobulin genes
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7 January 2021
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Molecular insights into the immunopathogenesis of follicular lymphoma
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7 January 2021
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Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes
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Germinal centers
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Clonal selection and learning in the antibody system
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7 January 2021
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Somatic hypermutation
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7 January 2021
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Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
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7 January 2021
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Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.
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Maturation of the immune response in germinal centers
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7 January 2021
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DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Both DNA strands of antibody genes are hypermutation targets
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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The targeting of somatic hypermutation
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells
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7 January 2021
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A plethora of lesion-replicating DNA polymerases
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7 January 2021
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Sloppier copier DNA polymerases involved in genome repair
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7 January 2021
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Cis-acting sequences that affect somatic hypermutation of Ig genes
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Somatic hypermutation: Another piece in the hypermutation puzzle
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Somatic hypermutation in the heavy chain locus correlates with transcription.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer
1 reference
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7 January 2021
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Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.
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7 January 2021
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BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci
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7 January 2021
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Cellular origin of human B-cell lymphomas.
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7 January 2021
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The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Mismatch repair and immunoglobulin gene hypermutation: did we learn something?
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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The role of DNA repair in somatic hypermutation of immunoglobulin genes
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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V(D)J hypermutation and DNA mismatch repair: vexed by fixation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Intraclonal generation of antibody mutants in germinal centres
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Severe attenuation of the B cell immune response in Msh2-deficient mice
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
based on heuristic
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TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene
1 reference
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based on heuristic
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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
1 reference
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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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A novel cytidine deaminase affects antibody diversity
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
based on heuristic
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Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Strand breaks in immunoglobulin gene hypermutation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5
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7 January 2021
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Identifiers
DOI
10.1016/S0952-7915(00)00206-5
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
PubMed ID
11228415
1 reference
stated in
Europe PubMed Central
PubMed ID
11228415
retrieved
6 July 2017
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