(Q32067279)

6 July 2017

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title

Towards an understanding of somatic hypermutation (English)

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6 July 2017

Jacobs H

1

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6 July 2017

Bross L

series ordinal

2

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6 July 2017

publication date

1 April 2001

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Current Opinion in Immunology

6 July 2017

published in

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6 July 2017

volume

13

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6 July 2017

issue

2

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6 July 2017

page(s)

208-218

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Specificity in V(D)J recombination: new lessons from biochemistry and genetics

6 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

The molecular basis of somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Molecular insights into the immunopathogenesis of follicular lymphoma

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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

1 reference

7 January 2021

Clonal selection and learning in the antibody system

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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

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https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Maturation of the immune response in germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

The targeting of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

A plethora of lesion-replicating DNA polymerases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Sloppier copier DNA polymerases involved in genome repair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Cis-acting sequences that affect somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Somatic hypermutation: Another piece in the hypermutation puzzle

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Cellular origin of human B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Mismatch repair and immunoglobulin gene hypermutation: did we learn something?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

The role of DNA repair in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

V(D)J hypermutation and DNA mismatch repair: vexed by fixation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Intraclonal generation of antibody mutants in germinal centres

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Severe attenuation of the B cell immune response in Msh2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

A novel cytidine deaminase affects antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

Strand breaks in immunoglobulin gene hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900206-5

7 January 2021

10.1016/S0952-7915(00)00206-5

Identifiers

DOI

1 reference

6 July 2017

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