(Q32173689)

English

6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

lymphoblastic leukemia

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Schmiegelow K

1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Bretton-Meyer U

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

publication date

1 January 2001

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

74-79

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy. Nordic Society for Pediatric Hematology and Oncology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

The clinical pharmacology of 6-mercaptopurine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

High-dose methotrexate as part of remission maintenance therapy for childhood acute lymphocytic leukemia: a Pediatric Oncology Group pilot study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Childhood leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and Pharmacokinetic Risk Factors for High-dose Methotrexate-induced Toxicity in Children with Acute Lymphoblastic Leukemia: A Logistic Regression Analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Physician compliance and relapse rates of acute lymphoblastic leukemia in children

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic Significance of Methotrexate and 6-Mercaptopurine Dosage During Maintenance Chemotherapy for Childhood Acute Lymphoblastic Leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of methotrexate on the bioavailability of oral 6-mercaptopurine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Purine de novo synthesis as the basis of synergism of methotrexate and 6-mercaptopurine in human malignant lymphoblasts of different lineages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Possible carcinogenic effect of 6-mercaptopurine on bone marrow stem cells: relation to thiopurine metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of 6-mercaptopurine, 6-thioguanine nucleotides, and 6-thiouric acid in biological fluids by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

A rapid, radiochemical-ligand binding assay for methotrexate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics, dose adjustments, and 6-mercaptopurine/methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Maintenance chemotherapy for childhood acute lymphoblastic leukemia: should dosage be guided by white blood cell counts?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical pharmacokinetics of commonly used anticancer drugs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Polyglutamation of methotrexate. Is methotrexate a prodrug?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Interrupted vs. continued maintenance therapy in childhood acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Methotrexate and 6-mercaptopurine maintenance therapy for childhood acute lymphoblastic leukemia: dose adjustments by white cell counts or by pharmacokinetic parameters?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401986

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2401986

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

ResearchGate publication ID

0 references

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