(Q33152239)

22 July 2017

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title

Atypical antipsychotics: from potassium channels to torsade de pointes and sudden death (English)

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22 July 2017

6

Wilhelm Haverkamp

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22 July 2017

Karine Titier

1

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22 July 2017

Pierre-Olivier Girodet

2

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22 July 2017

Hélène Verdoux

3

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22 July 2017

Mathieu Molimard

4

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22 July 2017

Bernard Bégaud

5

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22 July 2017

Malcolm Lader

7

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22 July 2017

Nicholas Moore

8

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22 July 2017

language of work or name

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1 January 2005

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22 July 2017

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22 July 2017

volume

28

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22 July 2017

issue

1

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22 July 2017

page(s)

35-51

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https://scigraph.springernature.com/pub.10.2165/00002018-200528010-00003

22 July 2017

exact match

0 references

cites work

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The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG.

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Psychotropic drugs and the ECG: focus on the QTc interval

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12 December 2020

Overdose of risperidone.

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12 December 2020

Torsade de pointes associated with the administration of intravenous haloperidol

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Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis.

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The use of atypical antipsychotics in the management of schizophrenia.

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Sudden cardiac death and antipsychotic drugs: do we know enough?

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Sudden death in a patient taking haloperidol

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Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation

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Cardiac safety parameters of olanzapine: comparison with other atypical and typical antipsychotics

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Prolongation of the QT interval and cardiac arrhythmias associated with cisapride: limitations of the pharmacoepidemiological studies conducted and proposals for the future

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Psychotropic drugs, cardiac arrhythmia, and sudden death

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The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

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Characterization of inhibition by risperidone of the inwardly rectifying K(+) current in pituitary GH(3) cells

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Long-term treatment with antipsychotic drugs in conventional doses prolonged QTc dispersion, but did not increase ventricular tachyarrhythmias in patients with schizophrenia in the absence of cardiac disease

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Risperidone prolongs cardiac action potential through reduction of K+ currents in rabbit myocytes

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[Sudden death following a single oral administration of haloperidol]

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Sudden Unexplained Death in a Psychiatric Patient Taking Thioridazine

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Aripiprazole in the treatment of schizophrenia: safety and tolerability in short-term, placebo-controlled trials

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12 December 2020

Distribution after repeated oral administration of different dose levels of risperidone and 9-hydroxy-risperidone in the brain and other tissues of rat.

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12 December 2020

Causes of the excess mortality of schizophrenia

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12 December 2020

Torsade de pointes caused by high-dose intravenous haloperidol in cardiac patients.

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12 December 2020

Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes

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12 December 2020

[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].

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12 December 2020

Investigation of the potential of clozapine to cause torsade de pointes

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12 December 2020

Sudden death following a single oral administration of haloperidol

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12 December 2020

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12 December 2020

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12 December 2020

Droperidol causes a dose-dependent prolongation of the QT interval

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12 December 2020

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12 December 2020

The antipsychotic drugs sertindole and pimozide block erg3, a human brain K(+) channel

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12 December 2020

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12 December 2020

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12 December 2020

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

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12 December 2020

The association between intravenous haloperidol and prolonged QT interval

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12 December 2020

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12 December 2020

Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin

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12 December 2020

Antipsychotics and QT prolongation

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12 December 2020

Efficacy and safety of aripiprazole and haloperidol versus placebo in patients with schizophrenia and schizoaffective disorder.

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12 December 2020

Ziprasidone: the fifth atypical antipsychotic

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12 December 2020

Myocarditis and cardiomyopathy associated with clozapine

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12 December 2020

Sudden death in phenothiazine therapy. (A clinicopathologic study of 12 cases).

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12 December 2020

Time dependent variability of QT dispersion after acute myocardial infarction and its relation to ventricular fibrillation: a prospective study

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12 December 2020

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12 December 2020

Arrhythmias and sudden death in patients taking antipsychotic drugs

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12 December 2020

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12 December 2020

The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: comparison with QT interval prolongation for assessment of risk of Torsades de Pointes

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12 December 2020

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12 December 2020

Pharmacokinetics and tissue distribution of olanzapine in rats

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12 December 2020

Fatal cardiac event following initiation of risperidone therapy

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12 December 2020

Post-mortem drug redistribution--a toxicological nightmare

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12 December 2020

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12 December 2020

A survey of sudden death associated with the use of antipsychotic or antidepressant drugs: 49 cases in Finland

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12 December 2020

Prolongation of the corrected QT and torsades de pointes cardiac arrhythmia associated with intravenous haloperidol in the medically ill.

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12 December 2020

In vivo and in vitro myocardial binding of risperidone and 9-hydroxyrisperidone

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12 December 2020

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

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12 December 2020

Determination of myocardium to plasma concentration ratios of five antipsychotic drugs: comparison with their ability to induce arrhythmia and sudden death in clinical practice.

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12 December 2020

Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study

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12 December 2020

Haloperidol-induced torsade de pointes

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12 December 2020

Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling

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12 December 2020

Haloperidol-induced torsades de pointes

1 reference

12 December 2020

Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose

1 reference

12 December 2020

Electrocardiographic changes with a neuroleptic: thioridazine

1 reference

12 December 2020

Biases affecting the proportional reporting ratio (PPR) in spontaneous reports pharmacovigilance databases: the example of sertindole

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12 December 2020

[Acute poisoning by risperidone and ionic and electrocardiographic changes]

1 reference

12 December 2020

Conduction disturbances associated with administration of butyrophenone antipsychotics in the critically ill: a review of the literature

1 reference

12 December 2020

Electrocardiographic changes in patients receiving neuroleptic medication.

1 reference

12 December 2020

Antipsychotics, HERG and sudden death

1 reference

12 December 2020

Thioridazine and sudden unexplained death in psychiatric in-patients.

1 reference

12 December 2020

Phenothiazines and Sudden Death

1 reference

12 December 2020

Overdose of ziprasidone

1 reference

12 December 2020

Mortality in a cohort of patients with schizophrenia: a record linkage study

1 reference

12 December 2020

10.2165/00002018-200528010-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

22 July 2017

1001704919

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1 reference