(Q33188464)

23 July 2017

title

Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein (English)

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23 July 2017

1 reference

Aslamuzzaman Kazi

1

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23 July 2017

Kenyon G Daniel

2

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23 July 2017

David M Smith

3

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23 July 2017

Nagi B Kumar

4

1 reference

23 July 2017

Q Ping Dou

5

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23 July 2017

language of work or name

English

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publication date

1 September 2003

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23 July 2017

published in

Biochemical Pharmacology

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23 July 2017

volume

66

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23 July 2017

issue

6

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23 July 2017

page(s)

965-976

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900414-3

23 July 2017

1 reference

Soy isoflavonoids and cancer -- metabolism at the target site

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Genistein and curcumin block TGF-beta 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes

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Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein

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Genistein inhibits NF-kappa B activation in prostate cancer cells

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Effect of genistein on topoisomerase activity and on the growth of [Val 12]Ha-ras-transformed NIH 3T3 cells

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Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells

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The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP

7 January 2021

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Effects of phytoestrogens on growth and DNA integrity in human prostate tumor cell lines: PC-3 and LNCaP.

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Genistein, a soy isoflavone, induces glutathione peroxidase in the human prostate cancer cell lines LNCaP and PC-3.

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Structure of 20S proteasome from yeast at 2.4 A resolution

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Functions of the proteasome: the lysis at the end of the tunnel

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Proteasome inhibitors as potential novel anticancer agents

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Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

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p53-dependent induction of apoptosis by proteasome inhibitors

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Proteasome-dependent regulation of p21WAF1/CIP1 expression

7 January 2021

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

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Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo

7 January 2021

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7 January 2021

The Protein Data Bank

1 reference

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Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

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Molecular docking of competitive phosphodiesterase inhibitors

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Modelling of factor Xa-inhibitor complexes: a computational flexible docking approach

7 January 2021

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Proteasome inhibitors: from research tools to drug candidates

7 January 2021

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Effects of soybean isoflavones on cell growth and apoptosis of the human prostatic cancer cell line LNCaP.

7 January 2021

1 reference

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p53 is involved in tumor necrosis factor-alpha-induced apoptosis in the human prostatic carcinoma cell line LNCaP.

7 January 2021

1 reference

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Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression

7 January 2021

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Different effects of genistein on molecular markers related to apoptosis in two phenotypically dissimilar breast cancer cell lines

7 January 2021

1 reference

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Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis

7 January 2021

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Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability

7 January 2021

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WAF1, a potential mediator of p53 tumor suppression

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

7 January 2021

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Comparison of plasma and urinary phytoestrogens in Japanese and Finnish women by time-resolved fluoroimmunoassay

7 January 2021

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Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako)

7 January 2021

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Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone

7 January 2021

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Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice

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10.1016/S0006-2952(03)00414-3

7 January 2021

Identifiers

DOI

1 reference

23 July 2017

1 reference