(Q33212646)

24 July 2017

title

The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. (English)

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24 July 2017

6

John S Lazo

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24 July 2017

1

Andreas Vogt

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24 July 2017

Aletheia Tamewitz

2

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24 July 2017

John Skoko

series ordinal

3

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24 July 2017

Rachel P Sikorski

series ordinal

4

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24 July 2017

Kenneth A Giuliano

series ordinal

5

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24 July 2017

language of work or name

English

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publication date

7 March 2005

1 reference

Journal of Biological Chemistry

24 July 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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24 July 2017

volume

280

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24 July 2017

issue

19

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24 July 2017

page(s)

19078-19086

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Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis

24 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Increased MAPK activity and MKP-1 overexpression in human gastric adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

21 January 2018

1 reference

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Spatial analysis of key signaling proteins by high-content solid-phase cytometry in Hep3B cells treated with an inhibitor of Cdc25 dual-specificity phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Cell-active dual specificity phosphatase inhibitors identified by high-content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources

21 January 2018

1 reference

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High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs

21 January 2018

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Two-dimensional goodness-of-fit testing in astronomy

21 January 2018

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A multidimensional version of the Kolmogorov–Smirnov test

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation

21 January 2018

1 reference

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Pharmacological activities of Chelidonium majus L. (Papaveraceae).

21 January 2018

1 reference

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Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Suppression of angiogenesis by the plant alkaloid, sanguinarine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1.

21 January 2018

1 reference

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Inhibition of eukaryote protein kinases by isoquinoline and oxazine alkaloids.

21 January 2018

1 reference

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Inhibitory effects of sanguinarine on monoamine oxidase activity in mouse brain

21 January 2018

1 reference

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Sanguinarine: A positive inotropic alkaloid which inhibits cardiac Na+,K+-ATPase

21 January 2018

1 reference

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The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death

21 January 2018

1 reference

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Apoptosis and drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Caspase-independent programmed cell death with necrotic morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501467200

21 January 2018

Identifiers

DOI

10.1074/JBC.M501467200

1 reference

24 July 2017

1 reference