(Q33221011)

24 July 2017

title

Construction of a functional transporter analysis system using MDR1 knockdown Caco-2 cells (English)

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24 July 2017

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Tomoko Watanabe

1

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24 July 2017

Reiko Onuki

2

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24 July 2017

Shinji Yamashita

3

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24 July 2017

Kazunari Taira

4

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24 July 2017

Yuichi Sugiyama

5

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24 July 2017

publication date

3 August 2005

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24 July 2017

published in

Pharmaceutical Research

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24 July 2017

volume

22

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24 July 2017

issue

8

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24 July 2017

page(s)

1287-1293

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Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump

24 July 2017

cites work

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12 December 2020

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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12 December 2020

An algorithm for selection of functional siRNA sequences.

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12 December 2020

Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4.

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12 December 2020

Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

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12 December 2020

Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein

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12 December 2020

P-glycoprotein expression and function in circulating blood cells from normal volunteers.

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12 December 2020

siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells

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12 December 2020

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein

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12 December 2020

New and better protocols for a short-term Caco-2 cell culture system

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12 December 2020

Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein

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12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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12 December 2020

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

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12 December 2020

Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption

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12 December 2020

Rational siRNA design for RNA interference

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12 December 2020

Rational use of in vitro P-glycoprotein assays in drug discovery

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo

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12 December 2020

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

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12 December 2020

The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules

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12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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12 December 2020

Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression

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12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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12 December 2020

Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis

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12 December 2020

Identification of functionally variant MDR1 alleles among European Americans and African Americans

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12 December 2020

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

12 December 2020

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans

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12 December 2020

Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)

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12 December 2020

Analysis of drug permeation across Caco-2 monolayer: implication for predicting in vivo drug absorption.

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12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

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12 December 2020

Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells

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12 December 2020

Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions

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12 December 2020

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

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12 December 2020

10.1007/S11095-005-5270-Z

Identifiers

DOI

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24 July 2017

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