(Q43850599)

27 November 2017

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein (English)

1 reference

27 November 2017

Y Adachi

1

1 reference

PubMed ID

11785684

27 November 2017

H Suzuki

series ordinal

2

1 reference

PubMed ID

11785684

27 November 2017

Y Sugiyama

series ordinal

3

1 reference

27 November 2017

1 December 2001

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27 November 2017

Pharmaceutical Research

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27 November 2017

18

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27 November 2017

1660-1668

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27 November 2017

12

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Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

27 November 2017

1 reference

12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

1 reference

12 December 2020

Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity

1 reference

12 December 2020

In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results

1 reference

12 December 2020

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

1 reference

12 December 2020

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

1 reference

12 December 2020

Pharmacological insights from P-glycoprotein knockout mice.

1 reference

12 December 2020

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

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12 December 2020

P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil

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12 December 2020

Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats.

1 reference

12 December 2020

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

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12 December 2020

6',7'-Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

1 reference

12 December 2020

Recent progress in P-glycoprotein research.

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12 December 2020

Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.

1 reference

12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

12 December 2020

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

1 reference

12 December 2020

Disposition of ivermectin and cyclosporin A in CF-1 mice deficient in mdr1a P-glycoprotein.

1 reference

12 December 2020

Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

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12 December 2020

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

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12 December 2020

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

12 December 2020

Co-operative binding sites for transported substrates in the multiple drug resistance transporter Mdr1

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12 December 2020

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase

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12 December 2020

P-Glycoprotein mediates the efflux of quinidine across the blood-brain barrier.

1 reference

12 December 2020

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

1 reference

12 December 2020

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

12 December 2020

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

1 reference

12 December 2020

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

12 December 2020

The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.

1 reference

12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

12 December 2020

Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability.

1 reference

12 December 2020

Transcellular transport of benzoic acid across Caco-2 cells by a pH-dependent and carrier-mediated transport mechanism

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1013358126640

1 reference

27 November 2017

1 reference

PubMed ID

11785684