(Q40923441)

24 September 2017

title

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery (English)

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24 September 2017

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Benet LZ

1

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24 September 2017

Izumi T

2

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24 September 2017

Zhang Y

3

1 reference

24 September 2017

Silverman JA

4

1 reference

24 September 2017

Wacher VJ

5

1 reference

24 September 2017

language of work or name

English

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publication date

1 November 1999

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Journal of Controlled Release

24 September 2017

published in

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24 September 2017

volume

62

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24 September 2017

issue

1-2

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24 September 2017

page(s)

25-31

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Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine*

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Tacrolimus oral bioavailability doubles with coadministration of ketoconazole

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Effects of ketoconazole on digoxin absorption and disposition in rat.

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7 January 2021

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

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https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900034-6

7 January 2021

Biochemistry of multidrug resistance mediated by the multidrug transporter

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7 January 2021

Expression of a multidrug-resistance gene in human tumors and tissues

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7 January 2021

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

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7 January 2021

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

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7 January 2021

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

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7 January 2021

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*

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7 January 2021

Cyclosporin-erythromycin interaction in renal transplant patients

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7 January 2021

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

1 reference

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7 January 2021

Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A

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7 January 2021

Metabolism of rifabutin in human enterocyte and liver microsomes: kinetic parameters, identification of enzyme systems, and drug interactions with macrolides and antifungal agents

1 reference

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7 January 2021

10.1016/S0168-3659(99)00034-6

Identifiers

DOI

1 reference

24 September 2017

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