(Q33223969)

24 July 2017

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title

Anti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor (English)

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24 July 2017

Kurt Vermeire

1

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Dominique Schols

object named as

Dominique Schols

series ordinal

2

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language of work or name

English

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publication date

1 October 2005

1 reference

Expert Opinion on Investigational Drugs

24 July 2017

published in

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24 July 2017

volume

14

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24 July 2017

issue

10

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24 July 2017

page(s)

1199-1212

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24 July 2017

cites work

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

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21 January 2018

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Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissocia

21 January 2018

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Solution structure of a circular-permuted variant of the potent HIV-inactivating protein cyanovirin-N: structural basis for protein stability and oligosaccharide interaction

21 January 2018

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The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.

21 January 2018

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Alpha-(1-3)- and alpha-(1-6)-D-mannose-specific plant lectins are markedly inhibitory to human immunodeficiency virus and cytomegalovirus infections in vitro

21 January 2018

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Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection

21 January 2018

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Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins

21 January 2018

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Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

21 January 2018

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In vivo administration to rhesus monkeys of a CD4-specific monoclonal antibody capable of blocking AIDS virus replication

21 January 2018

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A humanized, nondepleting anti-CD4 antibody that blocks virus entry inhibits virus replication in rhesus monkeys chronically infected with simian immunodeficiency virus

21 January 2018

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Development of anti-CD4 MAb hu5A8 for treatment of HIV-1 infection: preclinical assessment in non-human primates.

21 January 2018

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Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.

21 January 2018

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In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission

21 January 2018

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Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides

21 January 2018

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Effect of candidate vaginally-applied microbicide compounds on recognition of antigen by CD4+ and CD8+ T lymphocytes

21 January 2018

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A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women

21 January 2018

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Safety and acceptability of penile application of 2 candidate topical microbicides: BufferGel and PRO 2000 Gel: 3 randomized trials in healthy low-risk men and HIV-positive men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-binding domain of CD4.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

CD4 expression decrease by antisense oligonucleotides: inhibition of rat T CD4+ cell reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Specific CD4 down-modulating compounds with potent anti-HIV activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

The Anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

HIV requires multiple gp120 molecules for CD4-mediated infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.10.1199

Cyclotriazadisulfonamides: promising new CD4-targeted anti-HIV drugs

21 January 2018

1 reference

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10.1517/13543784.14.10.1199

21 January 2018

Identifiers

DOI

1 reference

24 July 2017

1 reference