(Q33233126)

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The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

8

object named as

Garth Powis

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

author name string

Amanda F Baker

1

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Tomislav Dragovich

2

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Wendy R Tate

3

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Ramesh K Ramanathan

4

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Denise Roe

5

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Chiu-Hsieh Hsu

6

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

D Lynn Kirkpatrick

7

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

publication date

1 February 2006

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Europe PubMed Central

PubMed publication ID

24 July 2017

Translational Research

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Europe PubMed Central

PubMed publication ID

24 July 2017

147

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

83-90

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility

1 reference

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Interactions amongst plasma retinol-binding protein, transthyretin and their ligands: implications in vitamin A homeostasis and transthyretin amyloidosis

1 reference

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21 June 2018

Characterization of the microheterogeneity of transthyretin in plasma and urine using SELDI-TOF-MS immunoassay

1 reference

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21 June 2018

Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity

1 reference

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Vascular endothelial growth factor-A is expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression.

1 reference

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The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers

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SELDI-TOF serum profiling for prognostic and diagnostic classification of breast cancers.

1 reference

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21 June 2018

Serum protein expression profiling for cancer detection: validation of a SELDI-based approach for prostate cancer

1 reference

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21 June 2018

Proteomic profiling in microdissected hepatocellular carcinoma tissue using ProteinChip technology.

1 reference

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21 June 2018

Serum diagnosis of pancreatic adenocarcinoma using surface-enhanced laser desorption and ionization mass spectrometry

1 reference

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21 June 2018

The thioredoxin system—From science to clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Proteinchip(R) surface enhanced laser desorption/ionization (SELDI) mass spectrometry: a novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures

1 reference

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21 June 2018

Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein

1 reference

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21 June 2018

Clinical potential of proteomics in the diagnosis of ovarian cancer

1 reference

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21 June 2018

ProteinChip clinical proteomics: computational challenges and solutions

1 reference

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Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival

1 reference

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21 June 2018

Properties and biological activities of thioredoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Physiological functions of thioredoxin and thioredoxin reductase

1 reference

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21 June 2018

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

1 reference

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21 June 2018

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

21 June 2018

The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1432091

31 October 2018

Clinical relevance of amphiregulin and VEGF in primary breast cancers

1 reference

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Serum proteomic profiles suggest celecoxib-modulated targets and response predictors

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31 October 2018

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival

1 reference

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Investigative proteomics: identification of an unknown plant virus from infected plants using mass spectrometry.

1 reference

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31 October 2018

The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.

1 reference

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31 October 2018

Expression of thioredoxin and glutaredoxin, redox-regulating proteins, in pancreatic cancer.

1 reference

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Thioredoxin-dependent redox regulation of p53-mediated p21 activation

1 reference

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Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

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based on heuristic

inferred from PubMed ID database lookup

Clinical usefulness of serum and plasma vascular endothelial growth factor in cancer patients: which is the optimal specimen?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

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Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-kappa B in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

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Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

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Elevated serum level of thioredoxin in patients with hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16459166

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Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

1 reference

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based on heuristic

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Identifiers

10.1016/J.LAB.2005.09.001

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

ResearchGate publication ID

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