(Q33234391)

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Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry

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PubMed publication ID

24 July 2017

Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry (English)

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Europe PubMed Central

PubMed publication ID

24 July 2017

author name string

Charles E Whitehurst

1

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24 July 2017

Naim Nazef

2

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24 July 2017

D Allen Annis

3

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Europe PubMed Central

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24 July 2017

Yongmin Hou

4

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24 July 2017

Denise M Murphy

5

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24 July 2017

Peter Spacciapoli

6

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24 July 2017

Zhiping Yao

7

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24 July 2017

Michael R Ziebell

8

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24 July 2017

Cliff C Cheng

9

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24 July 2017

Gerald W Shipps

10

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24 July 2017

Jason S Felsch

11

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24 July 2017

David Lau

12

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24 July 2017

Huw M Nash

13

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24 July 2017

publication date

20 February 2006

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24 July 2017

Journal of Biomolecular Screening

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24 July 2017

11

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24 July 2017

2

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24 July 2017

194-207

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24 July 2017

The state of GPCR research in 2004.

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Seven-transmembrane receptors

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Drug discovery: a historical perspective

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

G-protein-coupled receptor allosterism: the promise and the problem(s).

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Allosteric modulation of G protein-coupled receptors: perspectives and recent developments

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Allosteric modulators of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

G protein-coupled receptor allosterism and complexing

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Affinity Selection and Mass Spectrometry-Based Strategies to Identify Lead Compounds in Combinatorial Libraries

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Strategic use of affinity-based mass spectrometry techniques in the drug discovery process

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Chemical genetics: ligand-based discovery of gene function

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

A reagent-based strategy for the design of large combinatorial libraries: a preliminary experimental validation

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Pharmacological and structural integrity of muscarinic M2 acetylcholine receptors produced in Sf9 insect cells.

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence.

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Purification to homogeneity of an active opioid receptor from rat brain by affinity chromatography

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Pharmacological profile of selective muscarinic receptor antagonists on guinea-pig ileal smooth muscle

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors

1 reference

https://api.crossref.org/works/10.1177%2F1087057105284340

21 January 2018

Identifiers

10.1177/1087057105284340

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

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