(Q33236637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21 (English)

1 reference

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18 January 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

8

Dorothy Warburton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Chi-Ming Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Meirong Guo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Martha Salas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Nicole Schupf

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Wayne Silverman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Sameera Husain

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Harshwardhan Thaker

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Benjamin Tycko

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

15 March 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Gene expression analysis of cultured amniotic fluid cell with Down syndrome by DNA microarray

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Gene-dosage effects in Down syndrome and trisomic mouse models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Human chromosome 21q22.2-qter carries a gene(s) responsible for downregulation of mlc2a and PEBP in Down syndrome model mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Heart morphogenesis is not affected by overexpression of the Sh3bgr gene mapping to the Down syndrome heart critical region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Alopecia Areata: Autoimmunity—The Evidence Is Compelling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Global up-regulation of chromosome 21 gene expression in the developing down syndrome brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Protein expression in Down syndrome brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Cutaneous reactions associated with alpha interferon therapy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Early diagnosis of congenital heart disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Cutaneous aspects of Down syndrome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

The mouse brain transcriptome by SAGE: differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

The Down syndrome critical region.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Expression of type VI collagen in the developing mouse heart

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Early menopause in women with Down's syndrome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Down syndrome phenotypes: the consequences of chromosomal imbalance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Molecular mapping of twenty-four features of Down syndrome on chromosome 21.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Interferons, Mx genes, and resistance to influenza virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Functional Implications of Gene Dosage Effects in Trisomy 21

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Alopecia areata and mongolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

cDNA structures and regulation of two interferon-induced human Mx proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Abnormalities in the interferon response and immune systems in Down syndrome: studies in human trisomy 21 and mouse trisomy 16.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementatio

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Cellular ageing of Alzheimer's disease and down syndrome cells in culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Alopecia Areata and Down Syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Structure and polymorphism of the human gene for the interferon-induced p78 protein (MX1): evidence of association with alopecia areata in the Down syndrome region

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Alopecia areata during interferon alpha-2b/ribavirin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Dementia of the Alzheimer's type and accelerated aging in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Evidence for accelerated skin wrinkling among developmentally delayed individuals with Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Down syndrome congenital heart disease: a narrowed region and a candidate gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Restoration of DSCR1 to disomy in the trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Refining chromosomal region critical for Down syndrome-related heart defects with a case of cryptic 21q22.2 duplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Collagen type VI expression during cardiac development and in human fetuses with trisomy 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Expression of type VI collagen in the developing mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

An Updated Survey on Skin Conditions in Down Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Surgical experience with congenital heart disease in Down's syndrome.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1435874

Genetic variation in the COL6A1 region is associated with congenital heart defects in trisomy 21 (Down's syndrome)

31 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-7-24

Alopecia areata induced in C3H/HeJ mice by interferon-gamma: evidence for loss of immune privilege

21 January 2018

1 reference

12 December 2020

Transcriptome analysis of human autosomal trisomy

1 reference

12 December 2020

Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state

1 reference

12 December 2020

T-lymphocyte function and sensitivity to interferon in trisomy 21

1 reference

12 December 2020

Enhanced sensitivity of trisomy 21 monocytes to the maturation-inhibiting effect of interferon

1 reference

12 December 2020

Direct evidence that the gene product of the human chromosome 21 locus, IFRC, is the interferon-α receptor

1 reference

12 December 2020

Interferon induction of (2??5?) oligoisoadenylate synthetase in diploid and trisomy 21 human fibroblasts: Relation to dosage of the interferon receptor gene (IRFC)

1 reference

12 December 2020

Gene dosage and down-regulation of the α-interferon receptor

1 reference

12 December 2020

Myocardialization of the cardiac outflow tract

1 reference

12 December 2020

Results of surgical treatment of congenital heart defects in children with Down's syndrome

1 reference

12 December 2020

Alopecia areata induced by interferon alpha?

1 reference

12 December 2020

Localized interferon alfa-2b-induced alopecia

1 reference

12 December 2020

Outcome of fetuses diagnosed with atrioventricular septal defect

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2350-7-24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

16539728

1 reference