(Q33241594)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16648639%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity (English)

1 reference

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20 January 2020

3

1 reference

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20 January 2020

Milan Mrksich

6

1 reference

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20 January 2020

7

Geoffrey L Greene

1 reference

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20 January 2020

author name string

Robert W Hsieh

1

1 reference

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20 January 2020

Shyamala S Rajan

2

1 reference

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20 January 2020

Yuee Guo

4

1 reference

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20 January 2020

Eugene R DeSombre

5

1 reference

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20 January 2020

language of work or name

English

0 references

publication date

28 April 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16648639%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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20 January 2020

volume

281

1 reference

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20 January 2020

issue

26

1 reference

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20 January 2020

page(s)

17909-17919

1 reference

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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

20 January 2020

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Role of nuclear receptors in lung tumourigenesis

21 January 2018

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Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

21 January 2018

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Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern

21 January 2018

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Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta

21 January 2018

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Update on animal models developed for analyses of estrogen receptor biological activity

21 January 2018

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Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

21 January 2018

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Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

21 January 2018

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Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand

21 January 2018

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Dissecting physiological roles of estrogen receptor alpha and beta with potent selective ligands from structure-based design

21 January 2018

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Impact of isotype-selective estrogen receptor agonists on ovarian function

21 January 2018

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Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

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Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 January 2018

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Non-steroidal subtype selective estrogens

21 January 2018

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ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity

21 January 2018

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Structure-based design of estrogen receptor-beta selective ligands

21 January 2018

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A new series of estrogen receptor modulators that display selectivity for estrogen receptor beta

21 January 2018

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Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands

21 January 2018

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Understanding the selectivity of genistein for human estrogen receptor-beta using X-ray crystallography and computational methods

21 January 2018

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A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site

21 January 2018

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Estrogen receptor binding affinity and uterotrophic activity of triphenylhaloethylenes

21 January 2018

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Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta.

21 January 2018

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High throughput methods for gene cloning and expression.

21 January 2018

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Structural basis for the substrate specificity of tobacco etch virus protease

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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MOLREP: an Automated Program for Molecular Replacement

21 January 2018

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XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2018

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

21 January 2018

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Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

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21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

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The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

21 January 2018

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Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer.

21 January 2018

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Survey and assessment of mammalian estrogen biological assays for hazard characterization

21 January 2018

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Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta

21 January 2018

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Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors

21 January 2018

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Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists.

21 January 2018

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Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues

21 January 2018

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 January 2018

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Coregulator function: a key to understanding tissue specificity of selective receptor modulators

21 January 2018

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The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

21 January 2018

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Molecular basis for the subtype discrimination of the estrogen receptor-beta-selective ligand, diarylpropionitrile

21 January 2018

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Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor

21 January 2018

1 reference

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A novel estrogen receptor ligand template

21 January 2018

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Exploration of the bicyclo[3.3.1]nonane system as a template for the development of new ligands for the estrogen receptor.

21 January 2018

1 reference

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Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M513684200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16648639%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference