(Q33245411)

24 July 2017

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission (English)

1 reference

24 July 2017

Deborah J Anderson

5

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author name string

Richard A Cone

1

1 reference

24 July 2017

Timothy Hoen

2

1 reference

24 July 2017

Xixi Wong

3

1 reference

24 July 2017

Raed Abusuwwa

4

1 reference

24 July 2017

Thomas R Moench

6

1 reference

24 July 2017

1 June 2006

1 reference

24 July 2017

BMC Infectious Diseases

1 reference

24 July 2017

6

1 reference

24 July 2017

90

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2334-6-90

24 July 2017

0 references

cites work

Toxicity, inflammation, and anti-human immunodeficiency virus type 1 activity following exposure to chemical moieties of C31G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Comparative safety evaluation of the candidate vaginal microbicide C31G

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Herpes simplex virus: receptors and ligands for cell entry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Contraceptive effectiveness and safety of five nonoxynol-9 spermicides: a randomized trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Evaluations of unformulated and formulated dendrimer-based microbicide candidates in mouse and guinea pig models of genital herpes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Poly(sodium 4-styrene sulfonate): evaluation of a topical microbicide gel against herpes simplex virus type 2 and Chlamydia trachomatis infections in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Progesterone increases susceptibility and decreases immune responses to genital herpes infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Nonoxynol-9 for preventing vaginal acquisition of sexually transmitted infections by women from men.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Tests of Buffergel for contraception and prevention of sexually transmitted diseases in animal models.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Comparison of microbicides for efficacy in protecting mice against vaginal challenge with herpes simplex virus type 2, cytotoxicity, antibacterial properties, and sperm immobilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Nonoxynol-9 causes rapid exfoliation of sheets of rectal epithelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Inactivation of human immunodeficiency virus type 1 by nonoxynol-9, C31G, or an alkyl sulfate, sodium dodecyl sulfate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

A broad-spectrum microbicide with virucidal activity against sexually transmitted viruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Sulfated polysaccharides block chlamydia infection in vitro, but do not protect mice from vaginal inoculation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Tests of vaginal microbicides in the mouse genital herpes model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Sulfated polysaccharides extracted from sea algae as potential antiviral drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

The vaginal microflora of pig-tailed macaques and the effects of chlorhexidine and benzalkonium on this ecosystem.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Effects of nonoxynol-9 on vaginal microflora and chlamydial infection in a monkey model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Review: in vitro spermicidal tests

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

The inhibitory effect of spermicidal agents on replication of HSV-2 and HIV-1 in-vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Effect of polyanionic compounds on intracutaneous and intravaginal herpesvirus infection in mice: impact on the search for vaginal microbicides with anti-HIV activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Pathogenesis of genital herpes simplex virus infection in mice. IV. Quantitative aspects of viral latency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523343

Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Entry of inflammatory cells into the mouse vagina following application of candidate microbicides: comparison of detergent-based and sulfated polymer-based agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Disruption of the upper female reproductive tract epithelium by nonoxynol-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Nonoxynol-9 enhances rectal infection by herpes simplex virus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Lubricants containing N-9 may enhance rectal transmission of HIV and other STIs

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Microbicides--evaluating multiple formulations of C31G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Magnetic resonance imaging to determine the distribution of a vaginal gel: before, during, and after both simulated and real intercourse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Distribution of a spermicide containing Nonoxynol-9 in the vaginal canal and the upper female reproductive tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

In vivo distribution of a vaginal gel: MRI evaluation of the effects of gel volume, time and simulated intercourse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Monitoring of rabbit cornea response to dehydration stress by optical coherence tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

Lesson learned and dispelled myths: three-dimensional imaging of the human vagina

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2334-6-90

In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials

21 January 2018

1 reference

12 December 2020

Preventing disease by protecting the cervix: the unexplored promise of internal vaginal barrier devices

1 reference

12 December 2020

Nonoxynol-9 protects mice against vaginal transmission of genital herpes infections

1 reference

12 December 2020

Residence half-life of IgG administered topically to the mouse vagina

1 reference

12 December 2020

Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks

1 reference

12 December 2020

The topical microbicide PRO 2000 protects against genital herpes infection in a mouse model

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2334-6-90

1 reference

Dimensions Publication ID

24 July 2017

0 references

1 reference

24 July 2017

1 reference