(Q33245747)

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Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance

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scholarly article

1 reference

Europe PubMed Central

24 July 2017

Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance (English)

1 reference

Europe PubMed Central

24 July 2017

1 reference

based on heuristic

inferred from title

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

object named as

Sanjay Popat

1

0 references

Richard Houlston

object named as

Richard S Houlston

3

0 references

author name string

Richard Wort

2

1 reference

Europe PubMed Central

24 July 2017

language of work or name

0 references

publication date

5 June 2006

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

6

1 reference

Europe PubMed Central

24 July 2017

150

1 reference

Europe PubMed Central

24 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-6-150

0 references

The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

P53 abnormalities and outcomes in colorectal cancer: a systematic review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Systematic review of microsatellite instability and colorectal cancer prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Transcriptional activities of mutant p53: when mutations are more than a loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

The interaction of thymidylate synthase expression with p53-regulated signaling pathways in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Molecular predictors of survival after adjuvant chemotherapy for colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Characterization of a cis-acting regulatory element in the protein coding region of thymidylate synthase mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Genetic pathways in colorectal and other cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Mismatch repair proficiency and in vitro response to 5-fluorouracil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Cancer of the microsatellite mutator phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Identification of in vivo target RNA sequences bound by thymidylate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Identification of an RNA binding site for human thymidylate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Defects in replication fidelity of simple repeated sequences reveal a new mutator mechanism for oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Evaluation of immunohistochemical staining and activity of thymidylate synthase in cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Genetic alterations during colorectal-tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

p53: oncogene or anti-oncogene?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

The p53 tumour suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

p53 mutations in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

21 June 2018

Estimates of the worldwide incidence of eighteen major cancers in 1985.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Downregulation of p21/WAF1 expression by thymidylate synthase.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: phenotypic and genotypic analyses.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-150

21 January 2018

Associations between polymorphisms in the thymidylate synthase gene, the expression of thymidylate synthase mRNA and the microsatellite instability phenotype of colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

31 October 2018

p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

31 October 2018

p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1513242

31 October 2018

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The results of colorectal cancer treatment by p53 status: treatment-specific overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of antiavidin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mutant p53 in melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemically detected thymidylate synthase in colorectal cancer: an independent prognostic factor of survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase expression: an independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16753067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-6-150

1 reference

Europe PubMed Central

24 July 2017

Dimensions Publication ID

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release_bxiskramubarvgilvdhqqjetji

1 reference

https://api.fatcat.wiki/v0/release/bxiskramubarvgilvdhqqjetji

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

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