(Q33257634)

24 July 2017

An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF. (English)

1 reference

24 July 2017

1 reference

13

Bruce A Beutel

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24 July 2017

Kenneth M Comess

1

1 reference

24 July 2017

Mark E Schurdak

2

1 reference

24 July 2017

Martin J Voorbach

3

1 reference

24 July 2017

Michael Coen

4

1 reference

24 July 2017

Jonathan D Trumbull

5

1 reference

24 July 2017

Houjun Yang

6

1 reference

24 July 2017

Lan Gao

7

1 reference

24 July 2017

Hua Tang

8

1 reference

24 July 2017

Xueheng Cheng

9

1 reference

24 July 2017

Claude G Lerner

10

1 reference

24 July 2017

J Owen McCall

11

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24 July 2017

David J Burns

12

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24 July 2017

14 September 2006

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Journal of Biomolecular Screening

24 July 2017

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24 July 2017

11

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24 July 2017

7

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24 July 2017

743-754

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Hit and lead generation: beyond high-throughput screening

24 July 2017

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Designing screens: how to make your hits a hit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Antibacterial drug discovery in the post-genomics era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

High-density miniaturized thermal shift assays as a general strategy for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

High-throughput screening assay for the tunable selection of protein ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

NMR-based screening in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

High-throughput NMR-based screening with competition binding experiments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

MS/NMR: a structure-based approach for discovering protein ligands and for drug design by coupling size exclusion chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Analysis and screening of combinatorial libraries using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Applications of pulsed ultrafiltration-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Immunoaffinity Ultrafiltration with Ion Spray HPLC/MS for Screening Small-Molecule Libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Rapid methods for screening low molecular mass compounds non-covalently bound to proteins using size exclusion and mass spectrometry applied to inhibitors of human cytomegalovirus protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Early discovery drug screening using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Do structurally similar molecules have similar biological activity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Structure and function of the Mur enzymes: development of novel inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Structure-activity relationships of novel potent MurF inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Is there a difference between leads and drugs? A historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Nonleadlikeness and leadlikeness in biochemical screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Structure-based optimization of MurF inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Kinase inhibitors: not just for kinases anymore

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

Lead compounds discovered from libraries: part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057106289971

21 January 2018

Identifiers

DOI

10.1177/1087057106289971

1 reference

24 July 2017

1 reference