(Q33264731)

24 July 2017

title

Integrated siRNA design based on surveying of features associated with high RNAi effectiveness (English)

1 reference

24 July 2017

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Wuming Gong

1

1 reference

24 July 2017

Yongliang Ren

2

1 reference

24 July 2017

Qiqi Xu

3

1 reference

24 July 2017

Yejun Wang

4

1 reference

24 July 2017

Dong Lin

5

1 reference

24 July 2017

Haiyan Zhou

6

1 reference

24 July 2017

Tongbin Li

7

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24 July 2017

publication date

27 November 2006

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24 July 2017

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24 July 2017

volume

7

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24 July 2017

page(s)

516

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On the art of identifying effective and specific siRNAs

24 July 2017

cites work

1 reference

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Design of a genome-wide siRNA library using an artificial neural network

21 June 2018

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21 June 2018

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Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

21 June 2018

1 reference

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Local RNA target structure influences siRNA efficacy: a systematic global analysis

21 June 2018

1 reference

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Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

21 June 2018

1 reference

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RNA interference mediated in human primary cells via recombinant baculoviral vectors

21 June 2018

1 reference

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The energy profiling of short interfering RNAs is highly predictive of their activity.

21 June 2018

1 reference

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Sfold web server for statistical folding and rational design of nucleic acids

21 June 2018

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siRNA Selection Server: an automated siRNA oligonucleotide prediction server

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

DEQOR: a web-based tool for the design and quality control of siRNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Improving the efficiency of RNA interference in mammals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Rational siRNA design for RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Functional siRNAs and miRNAs Exhibit Strand Bias

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Asymmetry in the assembly of the RNAi enzyme complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

High-throughput selection of effective RNAi probes for gene silencing.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

siRNA function in RNAi: a chemical modification analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Statistical significance for genomewide studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Mfold web server for nucleic acid folding and hybridization prediction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Gene silencing in mammals by small interfering RNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Analysis of gene function in somatic mammalian cells using small interfering RNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

A system for stable expression of short interfering RNAs in mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Stability of RNA stem-loop structure and distribution of non-random structure in the human immunodeficiency virus (HIV-I).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retroviruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

siRecords: an extensive database of mammalian siRNAs with efficacy ratings.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Sequence characteristics of functional siRNAs

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

A comparison of siRNA efficacy predictors.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Filtering of ineffective siRNAs and improved siRNA design tool.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

How to design a highly effective siRNA.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Improved and automated prediction of effective siRNA.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

OptiRNAi, an RNAi design tool.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

An algorithm for selection of functional siRNA sequences.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698580

WT1 and BCR-ABL specific small interfering RNA have additive effects in the induction of apoptosis in leukemic cells

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17129386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Web-based design center for vector-based siRNA and siRNA cassette

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17129386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Picking a winner: new mechanistic insights into the design of effective siRNAs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17129386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2105-7-516

1 reference

journals/bmcbi/GongRXWLZL06

24 July 2017

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

24 July 2017

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