(Q33266187)

24 July 2017

title

Engineering embryonic stem cells with recombinase systems (English)

1 reference

Konstantinos Anastassiadis

24 July 2017

author

object named as

Konstantinos Anastassiadis

series ordinal

4

0 references

Harald von Melchner

series ordinal

3

object named as

Harald von Melchner

1 reference

24 July 2017

1

Frank Schnütgen

1 reference

24 July 2017

A Francis Stewart

2

1 reference

24 July 2017

language of work or name

English

0 references

publication date

1 January 2006

1 reference

24 July 2017

published in

Methods in Enzymology

1 reference

24 July 2017

volume

420

1 reference

24 July 2017

page(s)

100-136

1 reference

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

24 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Cre-mediated somatic site-specific recombination in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Inducible expression based on regulated recombination: a single vector strategy for stable expression in cultured cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Site-specific recombinase, R, encoded by yeast plasmid pSR1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Targeted integration of DNA using mutant lox sites in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

The knockout mouse project

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

The European dimension for the mouse genome mutagenesis program

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Improved properties of FLP recombinase evolved by cycling mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Crystal structure of a Flp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

New insight into site-specific recombination from Flp recombinase-DNA structures

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Inducible gene trapping with drug-selectable markers and Cre/loxP to identify developmentally regulated genes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

The lac operator-repressor system is functional in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Widespread recombinase expression using FLPeR (flipper) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Ligand-activated site-specific recombination in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Selection-marker-free modification of the murine beta-casein gene using a lox2272 [correction of lox2722] site

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Insertion of a foreign gene into the beta-casein locus by Cre-mediated site-specific recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Simplified mammalian DNA isolation procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

A genetic screen identifies novel non-compatible loxP sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Characterization of Cre-mediated cassette exchange after plasmid microinjection in fertilized mouse oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Nuclear targeting determinants of the phage P1 cre DNA recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Ligand-regulated site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Mice lacking all conventional MHC class II genes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

'Green mice' as a source of ubiquitous green cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Site-specific genomic integration produces therapeutic Factor IX levels in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Recombination. Pieces of the site-specific recombination puzzle

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Gene targeting in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

The Kw recombinase, an integrase from Kluyveromyces waltii

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Comparative kinetic analysis of FLP and cre recombinases: mathematical models for DNA binding and recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Identification of genes induced by factor deprivation in hematopoietic cells undergoing apoptosis using gene-trap mutagenesis and site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Inducible gene knockouts in the small intestinal and colonic epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Efficient FLP recombination in mouse ES cells and oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Predetermined chromosomal deletion encompassing the Nf-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Genomewide production of multipurpose alleles for the functional analysis of the mouse genome

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Temporally and spatially regulated somatic mutagenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Directed evolution of a recombinase for improved genomic integration at a native human sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Rapid generation of inducible mouse mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Codon-improved Cre recombinase (iCre) expression in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Diversity in the serine recombinases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Bacteriophage P1 cre gene and its regulatory region. Evidence for multiple promoters and for regulation by DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Selective disruption of genes transiently induced in differentiating mouse embryonic stem cells by using gene trap mutagenesis and site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Efficient removal of LoxP-flanked genes by electroporation of Cre-recombinase mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

A structural view of cre-loxp site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Cre-lox-regulated conditional RNA interference from transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Gene trap and gene inversion methods for conditional gene inactivation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Knockouts model the 100 best-selling drugs--will they model the next 100?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

Chromosome engineering in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2920007-7

7 January 2021

10.1016/S0076-6879(06)20007-7

Identifiers

DOI

1 reference

24 July 2017

1 reference