(Q33267003)

24 July 2017

title

DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH. (English)

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24 July 2017

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Rui Zhao

1

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24 July 2017

David Oxley

2

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24 July 2017

Trevor S Smith

3

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24 July 2017

George A Follows

4

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24 July 2017

Anthony R Green

5

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24 July 2017

Denis R Alexander

6

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24 July 2017

language of work or name

English

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publication date

1 January 2007

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24 July 2017

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24 July 2017

volume

5

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24 July 2017

issue

1

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24 July 2017

page(s)

e1

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Creative Commons Attribution 4.0 International

24 July 2017

copyright license

start time

19 December 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro

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21 June 2018

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21 June 2018

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Alterations of intracellular pH homeostasis in apoptosis: origins and roles

21 June 2018

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Bcl-XL down-regulation suppresses the tumorigenic potential of NPM/ALK in vitro and in vivo

21 June 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 June 2018

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 June 2018

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Deamidation and isoaspartate formation in proteins: unwanted alterations or surreptitious signals?

21 June 2018

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Structure and function of the NHE1 isoform of the Na+/H+ exchanger

21 June 2018

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Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger

21 June 2018

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21 June 2018

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Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

21 June 2018

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The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

21 June 2018

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Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

21 June 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 June 2018

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Regulation of myocardial Na+/H+ exchanger activity

21 June 2018

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Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

21 June 2018

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An informatics approach identifying markers of chemosensitivity in human cancer cell lines.

21 June 2018

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Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice

21 June 2018

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The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage

21 June 2018

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21 June 2018

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21 June 2018

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Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family

21 June 2018

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Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

21 June 2018

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Flow cytometric calibration of intracellular pH measurements in viable cells using mixtures of weak acids and bases.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1702560

Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67

21 June 2018

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Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

21 June 2018

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21 June 2018

Are cancer cells acidic?

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Delayed thymocyte development induced by augmented expression of p56lck

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1702560

A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation

21 June 2018

1 reference

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Asparagine deamidation perturbs antigen presentation on class II major histocompatibility complex molecules

31 October 2018

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Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides

31 October 2018

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Oncogenic tyrosine kinases, DNA repair and survival: the role of Bcl-xL deamidation in transformation and genotoxic therapies

31 October 2018

1 reference

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The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA.

31 October 2018

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An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation

31 October 2018

1 reference

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Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

31 October 2018

1 reference

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Structural integrity of histone H2B in vivo requires the activity of protein L-isoaspartate O-methyltransferase, a putative protein repair enzyme.

31 October 2018

1 reference

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Cell death in the absence of Bax and Bak

31 October 2018

1 reference

12 December 2020

Effects of Na+/H+ antiport and intracellular pH in the regulation of HL-60 cell apoptosis

1 reference

12 December 2020

Involvement of Bcl-X(L) deamidation in E1A-mediated cisplatin sensitization of ovarian cancer cells

1 reference

12 December 2020

Activation of the Na(+)/H(+) antiporter, Na+/HCO3(-)/CO3(2-) cotransporter, or Cl(-)/HCO3(-) exchanger in spontaneous thymocyte apoptosis

1 reference

12 December 2020

Suppression of Bcl-xL deamidation in human hepatocellular carcinomas

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.0050001

Identifiers

DOI

1 reference

24 July 2017

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24 July 2017

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