(Q35803867)

10 August 2017

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title

Alterations of intracellular pH homeostasis in apoptosis: origins and roles (English)

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10 August 2017

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Lagadic-Gossmann D

1

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10 August 2017

Huc L

series ordinal

2

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10 August 2017

Lecureur V

series ordinal

3

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10 August 2017

1 September 2004

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Cell Death & Differentiation

10 August 2017

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10 August 2017

11

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10 August 2017

953-961

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10 August 2017

9

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401466

10 August 2017

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cites work

Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Mitochondrial intermembrane proteins in cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Ion homeostasis and apoptosis

21 January 2018

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Endonuclease activation during apoptosis: the role of cytosolic Ca2+ and pH.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Mitochondria-dependent apoptosis and cellular pH regulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Regulation of acidification and apoptosis by SHP-1 and Bcl-2

21 January 2018

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Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

A permissive apoptotic environment: function of a decrease in intracellular superoxide anion and cytosolic acidification

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

A role for intracellular pH in membrane IgM-mediated cell death of human B lymphomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Nitric oxide as a bioregulator of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Neuronal intracellular pH directly mediates nitric oxide-induced programmed cell death.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Sodium overload through voltage-dependent Na(+) channels induces necrosis and apoptosis of rat superior cervical ganglion cells in vitro.

21 January 2018

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Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells

21 January 2018

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Blocking of acidosis-mediated apoptosis by a reduction of lactate dehydrogenase activity through antisense mRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Acidification of macrophage and fibroblast endocytic vesicles in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Apoptosis induced by Na+/H+ antiport inhibition activates the LEI/L-DNase II pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Inhibition of Bax channel-forming activity by Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Acid sphingomyelinase activation requires caspase-8 but not p53 nor reactive oxygen species during Fas-induced apoptosis in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Acidosis potentiates oxidative neuronal death by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Intracellular pH and the control of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Early mitochondrial hyperpolarization and intracellular alkalinization in lactacystin-induced apoptosis of retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Superoxide as a signal for increase in intracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

pH-dependent oxidant production following inhibition of the mitochondrial electron transport chain in pulmonary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Uncoupling cell shrinkage from apoptosis reveals that Na+ influx is required for volume loss during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Postmitochondrial regulation of apoptosis by bicarbonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Modulation of gene expression by extracellular pH variations in human fibroblasts: a transcriptomic and proteomic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Identification of deoxyribonuclease II as an endonuclease involved in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Activation of a low pH-dependent nuclease by apoptotic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Effect of pH, ionic charge, and osmolality on cytochrome c-mediated caspase-3 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Early transitory rise in intracellular pH leads to Bax conformation change during ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Possible involvement of a chloride-bicarbonate exchanger in apoptosis of endothelial cells and cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Detection of Mg(2+)-dependent endonuclease activity in myeloid leukemia cell nuclei capable of producing internucleosomal DNA cleavage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Different mode of cell death induced by calcium ionophore in human leukemia cell lines: possible role of constitutive endonuclease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Temperature-dependent arrest of neutrophil apoptosis. Failure of Bax insertion into mitochondria at 15 degrees C prevents the release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401466

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401466

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Dimensions Publication ID

10 August 2017

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1 reference