(Q34139313)

31 July 2017

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title

Mitochondria-dependent apoptosis and cellular pH regulation (English)

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31 July 2017

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1 reference

Matsuyama S

1

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PubMed ID

11175252

31 July 2017

Reed JC

series ordinal

2

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31 July 2017

1 December 2000

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Cell Death & Differentiation

31 July 2017

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31 July 2017

7

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31 July 2017

12

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31 July 2017

1155-1165

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400779

31 July 2017

0 references

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The mitochondrial electron transport and oxidative phosphorylation system

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Picture story. How proton pumps make ATP

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondria and neuronal survival

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Identification of a mitochondrial Na+/H+ exchanger

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The mechanism of proton transport mediated by mitochondrial uncoupling proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial cation transport: a progress report

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Toward the molecular structure of the mitochondrial channel, VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial control of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Apoptotic and anti-apoptotic synaptic signaling mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondria and neuronal glutamate excitotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Imaging the mitochondrial permeability transition pore in intact cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

An evolutionary perspective on apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Yeast as a tool for apoptosis research

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Role of oxidative phosphorylation in Bax toxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

A trace amount of the human pro-apoptotic factor Bax induces bacterial death accompanied by damage of DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Investigation of bax-induced release of cytochrome c from yeast mitochondria permeability of mitochondrial membranes, role of VDAC and ATP requirement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 family proteins as ion-channels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Comparison of the effects of bax -expression in yeast under fermentative and respiratory conditions: investigation of the role of adenine nucleotides carrier and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Role of mitochondria and C-terminal membrane anchor of Bcl-2 in Bax induced growth arrest and mortality in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Under respiratory growth conditions, Bcl-x(L) and Bcl-2 are unable to overcome yeast cell death triggered by a mutant Bax protein lacking the membrane anchor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The cytotoxic action of Bax on yeast cells does not require mitochondrial ADP/ATP carrier but may be related to its import to the mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The Mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The yeast ATP synthase subunit 4: structure and function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Identification of the subunits of F1F0-ATPase from bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mechanism responsible for oligomycin-induced occlusion of Na+ within Na/K-ATPase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Functional F1-ATPase essential in maintaining growth and membrane potential of human mitochondrial DNA-depleted rho degrees cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Use of intracellular pH and annexin-V flow cytometric assays to monitor apoptosis and its suppression by bcl-2 over-expression in hybridoma cell culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Apoptosis induced by IL-2 withdrawal is associated with an intracellular acidification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Regulation of acidification and apoptosis by SHP-1 and Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Intracellular acidification during apoptosis can occur in the absence of a nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Events in apoptosis. Acidification is downstream of protease activation and BCL-2 protection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Tumor necrosis factor receptor and Fas signaling mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Cytochrome c: can't live with it--can't live without it.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Purification and catalytic properties of human caspase family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Pro-caspase-3 is a major physiologic target of caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Biochemical characteristics of caspases-3, -6, -7, and -8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Postmitochondrial regulation of apoptosis during heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Preconditioning the human myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Mechanism of preconditioning. Ionic alterations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Importance of metabolic inhibition and cellular pH in mediating preconditioning contractile and metabolic effects in rat hearts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Acidic pH promotes dimerization of Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Channel formation by antiapoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Cytoprotection by Bcl-2 requires the pore-forming alpha5 and alpha6 helices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Ion channel activity of the BH3 only Bcl-2 family member, BID.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Changes in mitochondrial membrane potential during staurosporine-induced apoptosis in Jurkat cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Caspase-9 and APAF-1 form an active holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400779

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400779

1 reference

31 July 2017

1 reference

PubMed ID

11175252