(Q33267389)

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High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17184525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer (English)

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23 December 2019

Alexander Dobrovic

5

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23 December 2019

3

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23 December 2019

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Michael Krypuy

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23 December 2019

Genni M Newnham

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23 December 2019

Matthew Conron

4

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23 December 2019

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21 December 2006

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23 December 2019

1 reference

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23 December 2019

6

1 reference

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23 December 2019

295

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23 December 2019

https://scigraph.springernature.com/pub.10.1186/1471-2407-6-295

0 references

The Catalogue of Somatic Mutations in Cancer (COSMIC)

1 reference

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21 June 2018

Sensitive detection of KIT D816V in patients with mastocytosis

1 reference

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21 June 2018

Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins

1 reference

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21 June 2018

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

1 reference

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21 June 2018

Detection of rare mutant K-ras DNA in a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe

1 reference

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21 June 2018

Amplicon DNA melting analysis for mutation scanning and genotyping: cross-platform comparison of instruments and dyes

1 reference

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21 June 2018

Colorectal cancer prognosis: is it all mutation, mutation, mutation?

1 reference

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21 June 2018

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

1 reference

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21 June 2018

Erlotinib in lung cancer - molecular and clinical predictors of outcome

1 reference

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21 June 2018

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?

1 reference

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21 June 2018

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

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21 June 2018

Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Predictive factors for pancreatic cancer in patients with chronic pancreatitis in association with K-ras gene mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Sensitive and specific detection of K-ras mutations in colon tumors by short oligonucleotide mass analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Demonstration of preferential binding of SYBR Green I to specific DNA fragments in real-time multiplex PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

High-resolution genotyping by amplicon melting analysis using LCGreen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Diagnostic biochip array for fast and sensitive detection of K-ras mutations in stool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Molecular-clinical correlative studies in non-small cell lung cancer: application of a three-tiered approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Blocking oncogenic Ras signaling for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Implications and prognostic value of K-ras mutation for early-stage lung cancer in women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Mutation analyses of KRAS exon 1 comparing three different techniques: temporal temperature gradient electrophoresis, constant denaturant capillary electrophoresis and allele specific polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Restriction endonuclease-mediated selective polymerase chain reaction: a novel assay for the detection of K-ras mutations in clinical samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Detection of infrequent and multiple K-ras mutations in human tumors and tumor-adjacent tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Highly sensitive nonradioactive single-strand conformational polymorphism. Detection of Ki-ras mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

A simple salting out procedure for extracting DNA from human nucleated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

ras oncogenes in human cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

21 June 2018

EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

EGFR mutation status and prognosis for gefitinib treatment in Japanese lung cancer

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: a combined analysis of 881 cases.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Mutation detection in KRAS Exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Polymerase chain reaction-based K-ras mutation detection of pancreatic adenocarcinoma in routine cytology smears

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

A sensitive fluorescence monitor for the detection of activated Ras: total chemical synthesis of site-specifically labeled Ras binding domain of c-Raf1 immobilized on a surface

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Rapid, comprehensive screening of the human medium chain acyl-CoA dehydrogenase gene.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Sensitivity and specificity of single-nucleotide polymorphism scanning by high-resolution melting analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Human malignant melanoma: detection of BRAF- and c-kit-activating mutations by high-resolution amplicon melting analysis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Detection of c-kit exons 11- and 17-activating mutations in testicular seminomas by high-resolution melting amplicon analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Comparison of SYTO9 and SYBR Green I for real-time polymerase chain reaction and investigation of the effect of dye concentration on amplification and DNA melting curve analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Mutation scanning of the RET protooncogene using high-resolution melting analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-6-295

21 January 2018

Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

31 October 2018

Detection of K-ras mutations in lung carcinomas: relationship to prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

31 October 2018

Direct sequencing analysis of exon 1 of the c-K-ras gene shows a low frequency of mutations in human pancreatic adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

31 October 2018

K-ras point mutation detection in lung cancer: comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769510

31 October 2018

Detection of rare K-ras codon 12 mutations using allele-specific competitive blocker PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of Her-2/neu gene status in osteosarcoma by fluorescence in situ hybridization and multiplex and monoplex polymerase chain reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simplified Reverse Dot Blot Analyses for Detecting of ras Oncogene Mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRAF and c-kit gene copy number in mutation-positive malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinicopathological significance of Ki-ras point mutation and p21 expression in benign and malignant exocrine tumors of the human pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of p53 and K-ras genes as prognostic factors for non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of epidermal growth factor receptor and human epidermal growth factor receptor 2 activating mutations in lung adenocarcinoma by high-resolution melting amplicon analysis: correlation with gene copy number, protein expression, and hormone r

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Sensitive detection of K-ras oncogene codon 12 mutations by nested PCR using mismatched primers and selective digestion of non-mutated PCR fragments with restriction enzyme]

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of epidermal growth factor receptor (EGFR) and c-erbB-2 protein overexpression in adenocarcinoma of the uterine cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic value of the presence of mutations at the codons 12, 13, 61 of K-ras oncogene in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High sensitivity scanning of colorectal tumors and matched plasma DNA for mutations in APC, TP53, K-RAS, and BRAF genes with a novel DHPLC fluorescence detection platform

1 reference

https://pubmed.ncbi.nlm.nih.gov/17184525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-6-295

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17184525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17184525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17184525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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