(Q33270426)

24 July 2017

The iterative gramicidin s thioesterase catalyzes peptide ligation and cyclization (English)

1 reference

24 July 2017

Katharina M Hoyer

1

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24 July 2017

Christoph Mahlert

series ordinal

2

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24 July 2017

Mohamed A Marahiel

series ordinal

3

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24 July 2017

language of work or name

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1 January 2007

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24 July 2017

Chemistry and Biology

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24 July 2017

14

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24 July 2017

1

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24 July 2017

13-22

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The cyclization of peptides and depsipeptides

24 July 2017

1 reference

12 December 2020

Peptidyl thiophenols as substrates for nonribosomal peptide cyclases

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12 December 2020

Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase

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12 December 2020

Chemoenzymatic approach to enantiopure streptogramin B variants: characterization of stereoselective pristinamycin I cyclase from Streptomyces pristinaespiralis

1 reference

12 December 2020

Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase

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12 December 2020

Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors.

1 reference

12 December 2020

Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides

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12 December 2020

Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization.

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12 December 2020

Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species

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12 December 2020

Ligation of a synthetic peptide to the N terminus of a recombinant protein using semisynthetic protein trans-splicing.

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12 December 2020

Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

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12 December 2020

Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics

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12 December 2020

Loading peptidyl-coenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains

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12 December 2020

Ways of assembling complex natural products on modular nonribosomal peptide synthetases

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12 December 2020

Monitoring multiple active sites on thiotemplate enzymes in parallel: a molecular movie of yersiniabactin bioassembly

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12 December 2020

Biosynthesis of nonribosomal peptides1.

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12 December 2020

Evidence for a monomeric structure of nonribosomal Peptide synthetases

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12 December 2020

Biomimetic Synthesis of Gramicidin S and Analogues by Enzymatic Cyclization of Linear Precursors on Solid Support

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12 December 2020

Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases.

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12 December 2020

Optimized Protocol for Synthesis of Cyclic Gramicidin S: Starting Amino Acid Is Key to High Yield

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12 December 2020

Conformational study of gramicidin S using the phthalimide group as nuclear magnetic resonance marker

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12 December 2020

Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics.

1 reference

12 December 2020

Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the condensation domain.

1 reference

12 December 2020

Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

1 reference

12 December 2020

Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase

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12 December 2020

Enzymology of acyl chain macrocyclization in natural product biosynthesis

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12 December 2020

Structure–activity relationships of de novo designed cyclic antimicrobial peptides based on gramicidin S

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12 December 2020

The thioesterase domain of the fengycin biosynthesis cluster: a structural base for the macrocyclization of a non-ribosomal lipopeptide

1 reference

12 December 2020

Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases

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12 December 2020

On the mechanism of gramicidin S formation from intermediate peptides

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12 December 2020

Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141.

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2006.10.011

Identifiers

DOI

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24 July 2017

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