(Q33273472)

25 July 2017

title

EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors (English)

1 reference

25 July 2017

Yoh Dobashi

1

1 reference

25 July 2017

Shioto Suzuki

2

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25 July 2017

Eiichi Sato

3

1 reference

25 July 2017

Yoshiki Hamada

4

1 reference

25 July 2017

Takashi Yanagawa

5

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25 July 2017

Akishi Ooi

6

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25 July 2017

publication date

31 July 2009

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25 July 2017

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25 July 2017

volume

22

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25 July 2017

issue

10

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25 July 2017

page(s)

1328-1340

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The biology behind mTOR inhibition in sarcoma

25 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

The role of mTOR inhibitors for treatment of sarcomas

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Molecular pathology in sarcomas

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Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children's Oncology Group Study

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Aberration of epidermal growth factor receptor expression in bone and soft-tissue tumors: protein overexpression, gene amplification and activation of downstream molecules

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Expression of epidermal growth factor receptor, ERBB2 and KIT in adult soft tissue sarcomas: a clinicopathologic study of 281 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Involvement of epidermal growth factor receptor and downstream molecules in bone and soft tissue tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

mTOR, translation initiation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

The TOR pathway: a target for cancer therapy

21 January 2018

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TOR signaling in growth and metabolism

21 January 2018

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mTOR signaling: implications for cancer and anticancer therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Targeting the molecular target of rapamycin (mTOR).

21 January 2018

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Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

21 January 2018

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Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Diversity of epidermal growth factor receptor-mediated activation of downstream molecules in human lung carcinomas.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Critical and diverse involvement of Akt/mammalian target of rapamycin signaling in human lung carcinomas

21 January 2018

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Decreased expression of methyl methansulfonate and ultraviolet-sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma

21 January 2018

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

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The Measurement of Observer Agreement for Categorical Data

21 January 2018

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4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications

21 January 2018

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Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology

21 January 2018

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Effectiveness of cetuximab/gefitinib in the therapy of a sacral chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Mammalian target of rapamycin inhibitors in sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Regulation of ribosomal protein S6 kinases by ubiquitination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

mTOR signaling contributes to chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

Phosphorylation profiles of protein kinases in alveolar and embryonal rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

inferred from DOI database lookup

7 January 2021

based on heuristic

Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.104

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MODPATHOL.2009.104

1 reference

Dimensions Publication ID

25 July 2017

1017010059

0 references

1 reference