(Q33289555)

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Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development

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Europe PubMed Central

PubMed publication ID

25 July 2017

Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development (English)

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Europe PubMed Central

PubMed publication ID

25 July 2017

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Veronica Ulici

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Frank Beier

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Claudine G James

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Europe PubMed Central

PubMed publication ID

25 July 2017

Jan Tuckermann

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Europe PubMed Central

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25 July 2017

T Michael Underhill

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Europe PubMed Central

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25 July 2017

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1 July 2007

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Europe PubMed Central

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25 July 2017

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Europe PubMed Central

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25 July 2017

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Europe PubMed Central

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25 July 2017

205

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Europe PubMed Central

PubMed publication ID

25 July 2017

Identification, tissue expression, and glucocorticoid responsiveness of alternative first exons of the human glucocorticoid receptor

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21 June 2018

Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes

1 reference

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21 June 2018

Rapid glucocorticoid actions in the hypothalamus as a mechanism of homeostatic integration

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21 June 2018

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

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21 June 2018

Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment.

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21 June 2018

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

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21 June 2018

The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines.

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21 June 2018

Impaired growth plate chondrogenesis in children with chronic illnesses

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21 June 2018

Corticosteroid effects on cell signalling

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21 June 2018

Gene expression in skeletal tissues: application of laser capture microdissection

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21 June 2018

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21 June 2018

Identification by microarray analysis of aspartate aminotransferase and glutamine synthetase as glucocorticoid target genes in a mouse Schwann cell line

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21 June 2018

Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy

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21 June 2018

Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells

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Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

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21 June 2018

Immediate early genes of glucocorticoid action on the developing intestine.

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21 June 2018

Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype

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21 June 2018

Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways

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21 June 2018

Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3'-kinase signaling pathway

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21 June 2018

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage

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21 June 2018

Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.

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21 June 2018

Mechanisms of glucocorticoid signalling

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21 June 2018

Glucocorticoids synergize with IL-1beta to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells

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21 June 2018

VEGFA is necessary for chondrocyte survival during bone development

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21 June 2018

Evidence supporting dual, IGF-I-independent and IGF-I-dependent, roles for GH in promoting longitudinal bone growth.

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21 June 2018

Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength

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21 June 2018

Systemic and local regulation of the growth plate.

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21 June 2018

MAP kinases in chondrocyte differentiation.

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21 June 2018

Molecular ontogeny of the skeleton

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21 June 2018

Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins

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21 June 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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21 June 2018

Identification of a functional glucocorticoid response element in the promoter of the cyclin-dependent kinase inhibitor p57Kip2.

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21 June 2018

Developmental regulation of the growth plate

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21 June 2018

Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines

1 reference

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21 June 2018

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

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21 June 2018

Glucocorticoid effects on chondrogenesis, differentiation and apoptosis in the murine ATDC5 chondrocyte cell line

1 reference

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21 June 2018

Dexamethasone inhibits and thyroid hormone promotes differentiation of mouse chondrogenic ATDC5 cells

1 reference

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21 June 2018

Mechanisms of steroid impairment of growth

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21 June 2018

Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth

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21 June 2018

Reaching a genetic and molecular understanding of skeletal development

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21 June 2018

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21 June 2018

Glucorticoids and bone: some general remarks and some special observations in pediatric patients

1 reference

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21 June 2018

L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway

1 reference

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21 June 2018

Developmental control of chondrogenesis and osteogenesis

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21 June 2018

Suppression of growth plate chondrocyte proliferation by corticosteroids.

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21 June 2018

Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism

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21 June 2018

Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids

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21 June 2018

Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.

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21 June 2018

Nuclear structure--skeletal gene expression interrelationships

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21 June 2018

Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH- and IGF-I-receptor in cultured rat chondrocytes

1 reference

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21 June 2018

Inhibition of mitogen-activated protein kinase activity and proliferation of an early osteoblast cell line (MBA 15.4) by dexamethasone: role of protein phosphatases

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21 June 2018

Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by bone morphogenetic protein-6

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21 June 2018

SOX9 directly regulates the type-II collagen gene

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21 June 2018

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

1 reference

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21 June 2018

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

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21 June 2018

Regulation of cytokine and cytokine receptor expression by glucocorticoids

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21 June 2018

Stimulation of calcification of growth plate cartilage matrix vesicles by binding to type II and X collagens

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21 June 2018

Roles of the nucleational core complex and collagens (types II and X) in calcification of growth plate cartilage matrix vesicles.

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21 June 2018

Negative transcriptional regulation by nuclear receptors.

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21 June 2018

Chondrocyte differentiation

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21 June 2018

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

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21 June 2018

Glucocorticoid regulation of bone sialoprotein (BSP) gene expression. Identification of a glucocorticoid response element in the bone sialoprotein gene promoter

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21 June 2018

Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone

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21 June 2018

Regulation of bone sialoprotein gene transcription by steroid hormones

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21 June 2018

Hormonal control of skeletal growth

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21 June 2018

Regulation of gene expression of class I alcohol dehydrogenase by glucocorticoids

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21 June 2018

Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone

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21 June 2018

DNA regulatory elements for steroid hormones

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21 June 2018

Effects of dexamethasone and vitamin D3 on cartilage differentiation in a clonal chondrogenic cell population.

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21 June 2018

Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes

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21 June 2018

Dexamethasone acts locally to inhibit longitudinal bone growth in rabbits

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21 June 2018

Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B.

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31 October 2018

Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system

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31 October 2018

Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes

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31 October 2018

In vitro induction of directional differentiation of bone marrow mesenchymal stem cells towards chondrocytes

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31 October 2018

Identification of novel direct transcriptional targets of glucocorticoid receptor

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31 October 2018

Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development

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31 October 2018

Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells

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31 October 2018

Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis.

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31 October 2018

A probabilistic model for the extraction of expression levels from oligonucleotide arrays

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31 October 2018

Short-term glucocorticoid treatment of piglets causes changes in growth plate morphology and angiogenesis

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31 October 2018

p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation

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31 October 2018

IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation

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31 October 2018

Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling

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31 October 2018

Role of collagen type II and perlecan in skeletal development.

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31 October 2018

Regulation by glucocorticoids of cell differentiation and insulin-like growth factor binding protein production in cultured fetal rat nasal chondrocytes

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31 October 2018

Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes

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31 October 2018

Ultrastructural distribution of osteoadherin in rat bone shows a pattern similar to that of bone sialoprotein

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31 October 2018

Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy.

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31 October 2018

Apoptosis of terminally differentiated chondrocytes in culture.

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31 October 2018

Interactions between steroid hormones and insulin-like growth factor-I in rabbit chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929075

31 October 2018

Immunolocalization of receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin (OPG) in Meckel's cartilage compared with developing endochondral bones in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global gene profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation by glucocorticoid of the synthesis of cartilage-matrix proteoglycans produced by rabbit costal chondrocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the mouse type X collagen gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of type II and type X collagen synthesis in cultured growth plate chondrocytes by in situ hybridization: rapid induction of type X collagen in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hypothalamic somatostatin by glucocorticoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects and glucocorticoid potentiation of bone morphogenetic protein action during rat osteoblast differentiation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological and biochemical evidence for apoptosis in the terminal hypertrophic chondrocytes of the growth plate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further Observations on Programmed Cell Death in the Epiphyseal Growth Plate: Comparison of Normal and Dyschondroplastic Epiphyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapeutic agents used in the treatment of childhood malignancies have direct effects on growth plate chondrocyte proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic dissection of glucocorticoid receptor function in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The localization of the functional glucocorticoid receptor alpha in human bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone enhances SOX9 expression in chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of gene expression patterns during glucocorticoid-induced apoptosis using oligonucleotide arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukaemia inhibitory factor (lif) is expressed in hypertrophic chondrocytes and vascular sprouts during osteogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of osteoprotegerin (OPG) and its ligand (RANKL) mRNA and protein in femur and tibia of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoprotegerin (OPG) and RANKL expression and distribution in developing human craniomandibular joint

1 reference

https://pubmed.ncbi.nlm.nih.gov/17603917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2164-8-205

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-8-205

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

ResearchGate publication ID

0 references

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