(Q33290604)

25 July 2017

title

Engineered sarafotoxins as tissue inhibitor of metalloproteinases-like matrix metalloproteinase inhibitors (English)

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25 July 2017

5

Gregg B Fields

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25 July 2017

author name string

Janelle L Lauer-Fields

1

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25 July 2017

Mare Cudic

2

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25 July 2017

Shuo Wei

3

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25 July 2017

Frank Mari

4

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25 July 2017

Keith Brew

6

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25 July 2017

language of work or name

English

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publication date

10 July 2007

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Journal of Biological Chemistry

25 July 2017

published in

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25 July 2017

volume

282

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25 July 2017

issue

37

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25 July 2017

page(s)

26948-26955

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Long-sarafotoxins: characterization of a new family of endothelin-like peptides

25 July 2017

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Conformation of sarafotoxin-6b in aqueous solution determined by NMR spectroscopy and distance geometry.

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Endothelins are more sensitive than sarafotoxins to neutral endopeptidase: possible physiological significance

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The crystal structure of human endothelin

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Protein engineering of the tissue inhibitor of metalloproteinase 1 (TIMP-1) inhibitory domain. In search of selective matrix metalloproteinase inhibitors

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Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

21 January 2018

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Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

21 January 2018

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Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2

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Crystal structure of the catalytic domain of matrix metalloproteinase-1 in complex with the inhibitory domain of tissue inhibitor of metalloproteinase-1.

21 January 2018

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Residue 2 of TIMP-1 is a major determinant of affinity and specificity for matrix metalloproteinases but effects of substitutions do not correlate with those of the corresponding P1' residue of substrate

21 January 2018

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Involvement of a region near valine-69 of tissue inhibitor of metalloproteinases (TIMP)-1 in the interaction with matrix metalloproteinase 3 (stromelysin 1).

21 January 2018

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Substrate conformation modulates aggrecanase (ADAMTS-4) affinity and sequence specificity. Suggestion of a common topological specificity for functionally diverse proteases.

21 January 2018

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Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates

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Peptide libraries: determination of relative reaction rates of protected amino acids in competitive couplings

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Use of Edman degradation sequence analysis and matrix-assisted laser desorption/ionization mass spectrometry in designing substrates for matrix metalloproteinases

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Tissue sulfhydryl groups

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Ionization-reactivity relationships for cysteine thiols in polypeptides.

21 January 2018

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Disulfide bond structure of the AVR9 elicitor of the fungal tomato pathogen Cladosporium fulvum: evidence for a cystine knot

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Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity

21 January 2018

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Steps involved in activation of the complex of pro-matrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate

21 January 2018

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Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

21 January 2018

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

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1H NMR studies of sarafotoxin SRTb, a nonselective endothelin receptor agonist, and IRL 1620, an ETB receptor-specific agonist

21 January 2018

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E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)

21 January 2018

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Reactive site-modified tissue inhibitor of metalloproteinases-2 inhibits the cell-mediated activation of progelatinase A.

21 January 2018

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The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

21 January 2018

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

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Increased backbone mobility in beta-barrel enhances entropy gain driving binding of N-TIMP-1 to MMP-3.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M611612200

1 reference

25 July 2017

1 reference