(Q33296885)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17784787%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

In vitro and in vivo neurotoxicity of prion protein oligomers (English)

1 reference

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5 January 2020

0 references

1 reference

1 reference

11

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5 January 2020

author name string

Steve Simoneau

1

1 reference

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5 January 2020

Human Rezaei

2

1 reference

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5 January 2020

Nicole Salès

3

1 reference

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5 January 2020

Gunnar Kaiser-Schulz

4

1 reference

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5 January 2020

Maxime Lefebvre-Roque

5

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5 January 2020

Catherine Vidal

6

1 reference

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5 January 2020

Jean-Guy Fournier

7

1 reference

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5 January 2020

Julien Comte

8

1 reference

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5 January 2020

Franziska Wopfner

9

1 reference

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5 January 2020

Jeanne Grosclaude

10

1 reference

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5 January 2020

Corinne Ida Lasmézas

12

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5 January 2020

publication date

1 August 2007

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5 January 2020

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5 January 2020

volume

3

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5 January 2020

issue

8

1 reference

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5 January 2020

page(s)

e125

1 reference

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Creative Commons Attribution 4.0 International

5 January 2020

copyright license

start time

31 August 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Diversity in prion protein oligomerization pathways results from domain expansion as revealed by hydrogen/deuterium exchange and disulfide linkage

1 reference

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Accumulation of prion protein in the brain that is not associated with transmissible disease

21 June 2018

1 reference

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Lethal recessive myelin toxicity of prion protein lacking its central domain

21 June 2018

1 reference

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 June 2018

1 reference

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A specific amyloid-beta protein assembly in the brain impairs memory

21 June 2018

1 reference

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Evidence that Perutz's double-beta-stranded subunit structure for beta-amyloids also applies to their channel-forming structures in membranes

21 June 2018

1 reference

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21 June 2018

1 reference

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Anchorless prion protein results in infectious amyloid disease without clinical scrapie

21 June 2018

1 reference

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An unusual soluble beta-turn-rich conformation of prion is involved in fibril formation and toxic to neuronal cells.

21 June 2018

1 reference

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Synthetic mammalian prions

21 June 2018

1 reference

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Evidence for assembly of prions with left-handed beta-helices into trimers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Protein folding and misfolding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

21 June 2018

1 reference

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

21 June 2018

1 reference

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 June 2018

1 reference

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Molecular biology of prions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Toxic proteins in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Doppel-induced cerebellar degeneration in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

PrPC directly interacts with proteins involved in signaling pathways

21 June 2018

1 reference

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Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

21 June 2018

1 reference

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Studies on peptide fragments of prion proteins.

21 June 2018

1 reference

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High yield purification and physico-chemical properties of full-length recombinant allelic variants of sheep prion protein linked to scrapie susceptibility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 June 2018

1 reference

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Evolution of a strain of CJD that induces BSE-like plaques

21 June 2018

1 reference

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Apoptosis-mediated neurotoxicity induced by beta-amyloid and PrP fragments.

21 June 2018

1 reference

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Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Neuropathology of spongiform encephalopathies in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Novel proteinaceous infectious particles cause scrapie

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Western blot detection of scrapie-associated fibril protein in tissues outside the central nervous system from preclinical scrapie-infected mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

A 'unified theory' of prion propagation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Biomedicine. An end to the prion debate? Don't count on it.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Scrapie-specific neuronal lesions are independent of neuronal PrP expression

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Formation of critical oligomers is a key event during conformational transition of recombinant syrian hamster prion protein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Channels formed with a mutant prion protein PrP(82-146) homologous to a 7-kDa fragment in diseased brain of GSS patients

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Distinct profiles of PrPd immunoreactivity in the brain of scrapie- and BSE-infected sheep: implications for differential cell targeting and PrP processing

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Amyloidogenic unfolding intermediates differentiate sheep prion protein variants

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Pathway complexity of prion protein assembly into amyloid

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Chaperone overload is a possible contributor to 'civilization diseases'.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Folding of prion protein to its native alpha-helical conformation is under kinetic control

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Normal host prion protein necessary for scrapie-induced neurotoxicity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Neurotoxicity of a prion protein fragment

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Transmission of fatal familial insomnia to laboratory animals

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959381

Oligomerization of the human prion protein proceeds via a molten globule intermediate

10 December 2018

1 reference

12 December 2020

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

1 reference

12 December 2020

Chaperone function and chaperone overload in the aged. A preliminary analysis

1 reference

12 December 2020

Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein

1 reference

12 December 2020

Sequential generation of two structurally distinct ovine prion protein soluble oligomers displaying different biochemical reactivities

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.0030125

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17784787%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17784787%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

17784787

1 reference