(Q33301880)

25 July 2017

title

Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure (English)

1 reference

25 July 2017

Bradford G Hill

2

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author name string

Jianzhu Luo

1

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25 July 2017

Yan Gu

3

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25 July 2017

Jian Cai

4

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25 July 2017

Sanjay Srivastava

5

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25 July 2017

Aruni Bhatnagar

6

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25 July 2017

Sumanth D Prabhu

7

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25 July 2017

language of work or name

1 reference

5 October 2007

1 reference

American Journal of Physiology Heart and Circulatory Physiology

25 July 2017

published in

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25 July 2017

volume

293

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25 July 2017

issue

6

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25 July 2017

page(s)

H3673-84

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Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

25 July 2017

cites work

1 reference

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Molecular and cellular mechanisms of myocardial stunning

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Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

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Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair

21 January 2018

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Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment

21 January 2018

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Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols

21 January 2018

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Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin

21 January 2018

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Hazardous air pollutants and asthma

21 January 2018

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Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

21 January 2018

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Acrolein induces oxidative stress in brain mitochondria

21 January 2018

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Prolonged oxidative stress inverts the cardiac force-frequency relation: role of altered calcium handling and myofilament calcium responsiveness

21 January 2018

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Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells

21 January 2018

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Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans

21 January 2018

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Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients.

21 January 2018

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Navigating the signalling network in mouse cardiac myocytes

21 January 2018

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Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.

21 January 2018

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Lipid peroxidation-derived aldehydes and oxidative stress in the failing heart: role of aldose reductase

21 January 2018

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Downregulation of CuZn-superoxide dismutase contributes to beta-adrenergic receptor-mediated oxidative stress in the heart

21 January 2018

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Structural and kinetic determinants of aldehyde reduction by aldose reductase

21 January 2018

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Comparative toxicity of allylamine and acrolein in cultured myocytes and fibroblasts from neonatal rat heart

21 January 2018

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Current status of acrolein as a lipid peroxidation product

21 January 2018

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Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins

21 January 2018

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Protein-bound acrolein: potential markers for oxidative stress

21 January 2018

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Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction

21 January 2018

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Proteomics of ischemia/reperfusion injury in rabbit myocardium reveals alterations to proteins of essential functional systems

21 January 2018

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Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry

21 January 2018

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Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria

21 January 2018

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10.1152/AJPHEART.00284.2007

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference