(Q33313393)

25 July 2017

title

In the era of systematic reviews, does the size of an individual trial still matter (English)

1 reference

25 July 2017

1 reference

1

Gordon H Guyatt

1 reference

25 July 2017

3

Diana Elbourne

1 reference

25 July 2017

2

Edward J Mills

1 reference

25 July 2017

language of work or name

English

0 references

publication date

1 January 2008

1 reference

25 July 2017

1 reference

25 July 2017

volume

5

1 reference

25 July 2017

issue

1

1 reference

25 July 2017

page(s)

e4

1 reference

Creative Commons Attribution 4.0 International

25 July 2017

copyright license

start time

3 January 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Randomized trials stopped early for benefit: a systematic review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Validity of composite end points in clinical trials

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Discrepancies among megatrials

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Size is everything--large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

NIH clinical trials and publication bias

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Absence of evidence is not evidence of absence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Ethical issues in stopping randomized trials early because of apparent benefit.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

The continuing unethical conduct of underpowered clinical trials.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Statistics and ethics in medical research: III How large a sample?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174963

Discussion Sections in Reports of Controlled Trials Published in General Medical Journals

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18177203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PMED.0050004

1 reference

25 July 2017

1 reference

25 July 2017

1 reference