(Q33322191)

25 July 2017

title

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

25 July 2017

main subject

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author name string

Edor Kabashi

1

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25 July 2017

Jeffrey N Agar

2

1 reference

25 July 2017

Yu Hong

3

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25 July 2017

David M Taylor

4

1 reference

25 July 2017

Sandra Minotti

5

1 reference

25 July 2017

Denise A Figlewicz

6

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25 July 2017

Heather D Durham

7

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25 July 2017

language of work or name

English

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publication date

1 June 2008

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Journal of Neurochemistry

25 July 2017

number of pages

14

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based on heuristic

inferred from page(s)

published in

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25 July 2017

volume

105

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25 July 2017

issue

6

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25 July 2017

page(s)

2353-2366

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The proteasome: paradigm of a self-compartmentalizing protease

25 July 2017

cites work

1 reference

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Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion

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Impact of ageing on proteasome structure and function in human lymphocytes

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Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.

21 January 2018

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Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis

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Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

21 January 2018

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Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

21 January 2018

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Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

21 January 2018

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CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

21 January 2018

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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

21 January 2018

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21 January 2018

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Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

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Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

21 January 2018

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Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

10.1111/J.1471-4159.2008.05317.X

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference