(Q33334739)

25 July 2017

title

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome (English)

1 reference

25 July 2017

Colin J Daniel

1

1 reference

25 July 2017

Brian Conti

series ordinal

2

1 reference

25 July 2017

Arthur E Johnson

series ordinal

3

1 reference

25 July 2017

William R Skach

series ordinal

4

1 reference

25 July 2017

language of work or name

English

0 references

publication date

13 May 2008

1 reference

Journal of Biological Chemistry

25 July 2017

published in

1 reference

25 July 2017

volume

283

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25 July 2017

issue

30

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25 July 2017

page(s)

20864-20873

1 reference

A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization

25 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Molecular mechanisms of aquaporin biogenesis by the endoplasmic reticulum Sec61 translocon

21 June 2018

1 reference

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Ribosome exit tunnel can entropically stabilize alpha-helices

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Membrane-protein integration and the role of the translocation channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Cotranslational integration and initial sorting at the endoplasmic reticulum translocon of proteins destined for the inner nuclear membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Protein translocons: multifunctional mediators of protein translocation across membranes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Structure of the mammalian ribosome-channel complex at 17A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Aquaporin water channels--from atomic structure to clinical medicine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

A new role for BiP: closing the aqueous translocon pore during protein integration into the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Structural basis of water-specific transport through the AQP1 water channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Cotranslational folding--omnia mea mecum porto?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Different conformations of nascent polypeptides during translocation across the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Structure of a glycerol-conducting channel and the basis for its selectivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

The translocon: a dynamic gateway at the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

A two-step recognition of signal sequences determines the translocation efficiency of proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Transmembrane orientation of signal-anchor proteins is affected by the folding state but not the size of the N-terminal domain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Guanosine triphosphate promotes the post-translational integration of opsin into the endoplasmic reticulum membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Protein translocation across the endoplasmic reticulum membrane: identification by photocross-linking of a 39-kD integral membrane glycoprotein as part of a putative translocation tunnel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Fluorescence characterization of the environment encountered by nascent polyalanine and polyserine as they exit Escherichia coli ribosomes during translation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Bidirectional movement of a nascent polypeptide across microsomal membranes reveals requirements for vectorial translocation of proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

What drives the translocation of proteins?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2475691

Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Architecture of the protein-conducting channel associated with the translating 80S ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Different conformations of nascent peptides on ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Folding zones inside the ribosomal exit tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Translation arrest requires two-way communication between a nascent polypeptide and the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Architecture of the Ribosome–Channel Complex Derived from Native Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

The Geometry of the Ribosomal Polypeptide Exit Tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803517200

Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel

21 January 2018

1 reference

12 December 2020

Uncoupling translocation from translation: implications for transport of proteins across membranes

1 reference

12 December 2020

The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation

1 reference

12 December 2020

A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane

1 reference

12 December 2020

The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process

1 reference

12 December 2020

Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration

1 reference

12 December 2020

Active and passive displacement of transmembrane domains both occur during opsin biogenesis at the Sec61 translocon

1 reference

12 December 2020

Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly

1 reference

12 December 2020

BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation

1 reference

12 December 2020

Secondary structure formation of a transmembrane segment in Kv channels

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M803517200

1 reference

25 July 2017

1 reference

25 July 2017

1 reference